Stroke Flashcards
What are the classic symptoms of a stroke?
Sudden onset of:
• Numbness or weakness of face, arm, or leg (especially one side)
• Confusion, trouble speaking or understanding speech
• Trouble seeing in one or both eyes
• Trouble walking, dizziness, loss of balance or coordination
• Severe headache with no known cause (hemorrhagic stroke)
• May include: stiff neck, facial pain, pain between the eyes, vomiting, altered consciousness
What does FAST stand for in stroke recognition?
• Face – Is it drooping when smiling?
• Arms – Can they raise both?
• Speech – Is it slurred or jumbled?
• Time – Call 911 if these symptoms appear
What additional stroke symptoms may females experience?
Females may have:
• Fainting
• Seizures
• Sudden hiccups
• Sudden nausea
• Chest, jaw, or neck pain
• Fatigue
• Shortness of breath
• Racing heartbeat
• Anxiety or “feeling something isn’t right”
• General weakness (not just one-sided)
• Fever
What are the signs and symptoms of an anterior cerebral artery stroke?
• Spastic paralysis of contralateral foot/leg
• Spastic paresis of contralateral arm
• Sensory loss in toes, foot, leg
• Cognitive issues: decision-making problems, lack of spontaneity, distractibility, slow thinking
• Aphasia (depends on hemisphere affected)
• Urinary incontinence
• Mood & cognitive disorders
What are the signs and symptoms of a middle cerebral artery stroke?
• Contralateral spastic hemiplegia (face & arm)
• Contralateral sensory impairment
• Aphasia
• Homonymous hemianopia
• Altered consciousness (confusion → coma)
• Inability to turn eyes toward paralyzed side
• Denial of paralysis (hemi-inattention)
• Potential cognitive deficits:
- Acalculia (math difficulties)
- Agraphia (writing impairment)
- Alexia (reading impairment)
- Finger agnosia
- Left-right confusion
• Vasomotor paresis & instability
What are the signs and symptoms of a posterior cerebral artery stroke?
• Homonymous hemianopia (loss of vision on one side)
• Other visual defects:
- Color blindness
- Loss of central vision
- Visual hallucinations
• Memory deficits
• Perseveration (repetitive verbal/motor responses)
What are the signs of a stroke with thalamus involvement?
• Loss of all sensory modalities
• Spontaneous pain
• Intentional tremor
• Mild hemiparesis
• Aphasia
What are the signs of a stroke with cerebral peduncle involvement?
• Oculomotor nerve palsy
• Contralateral hemiplegia
What are the signs of a stroke in the basilar & vertebral arteries?
• Visual disturbances: diplopia
• Dystaxia (coordination problems)
• Vertigo
• Dysphagia (trouble swallowing)
• Dysphonia (voice changes)
How does age affect stroke risk?
Stroke risk increases with age, especially >55
• Males have higher stroke risk at younger ages
• Females have more strokes than males at older ages
How does sex affect stroke risk?
• Females have more strokes & higher mortality than males
• Risk factors for females:
- Pregnancy
- History of preeclampsia/eclampsia or gestational diabetes
- Oral contraceptives (esp. with smoking)
- Menopause & post-menopausal hormone therapy
How does race affect stroke risk?
African-Americans & Hispanics have a higher risk of stroke-related death than Caucasians
How does a previous TIA, stroke, or MI affect future stroke risk?
Having a TIA = 10x higher stroke risk compared to someone who hasn’t had one
How does sickle cell disease (SCD) increase stroke risk?
• Mainly affects African-American & Hispanic children
• Sickled RBCs reduce oxygen delivery, increasing stroke risk
• Cells stick to blood vessel walls, causing blockages leading to stroke
What is the most significant controllable risk factor for stroke?
Hypertension
• A leading cause of stroke
• Most significant modifiable risk factor
Why is diabetes mellitus a stroke risk factor?
• Independent risk factor
• Many with diabetes also have:
- High blood pressure
- High cholesterol
- Overweight/obesity
- These factors further increase stroke risk
How does hypercholesteremia contribute to stroke risk?
• Excess LDL (“bad” cholesterol) increases stroke risk
• May be due to diet or genetics
• Leads to atherosclerosis and blood vessel blockages
How does carotid artery disease increase stroke risk?
• Narrowing of carotid arteries due to atherosclerosis
• May become blocked by a blood clot, leading to stroke
How does peripheral artery disease (PAD) increase stroke risk?
• Atherosclerosis in peripheral arteries raises risk
• Increases likelihood of carotid artery disease
How does atrial fibrillation (AFib) increase stroke risk?
• Causes irregular heartbeats
• Can lead to blood clots traveling to the brain
What heart diseases increase stroke risk?
• Congestive heart failure
• Valve diseases
• Dilated cardiomyopathy
How does smoking increase stroke risk?
• Nicotine & carbon monoxide damage blood vessels
• Risk greatly increases when combined with birth control
• African Americans who smoke have double the stroke risk compared to non-smokers
How does physical inactivity increase stroke risk?
Leads to higher risk of:
• Stroke
• Heart disease
• Overweight/obesity
• High blood pressure
• High cholesterol
• Diabetes
How does obesity increase stroke risk?
• Linked to high blood pressure, diabetes, heart disease, and stroke
What other factors increase stroke risk?
• Alcohol abuse
• Drug abuse
• COVID-19
• Sleep issues:
- Insufficient sleep
- Sleep apnea
What are the main goals of post-stroke treatment?
- Prevent recurrent stroke
- Prevent medical complications
- Promote fullest possible recovery of function
When is the risk of stroke recurrence the highest?
• First week after stroke or TIA
• Early implementation of antiplatelet drugs or anticoagulants (e.g., warfarin) is critical in cardioembolic stroke
What percentage of stroke survivors will have another stroke within the first year?
Almost 25% (a quarter)
What is the most effective way to prevent long-term stroke recurrence?
Aggressive reduction of modifiable risk and behavioral factors, especially:
• Smoking
• Hypertension
• Diabetes
• Hyperlipidemia (e.g., hypercholesteremia)