stress and anxiety Flashcards

1
Q

what are different types of anxiety disorders?

A
  • seperation
  • GAD
  • specific phobia
  • agoraphobia
  • panic attack/disorder
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2
Q

what are some clinical descriptions of anxiety based on DSM-V?

A

for last 6 months…

  • worrying excessively
  • signs of physical tension
  • problems with attention/concentration
  • suffer depressed mood
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3
Q

what are some physical symptoms of GAD?

A
  • muscle tension
  • fatigue
  • edginess
  • restlessness
  • difficulty sleeping
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4
Q

what are some functions of the medial cerebral cortex?

A
  • planning
  • decision making
  • reward processing
  • predicting consequences
  • regulate impulses, emotions and behaviour
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5
Q

where is the limbic system located?

A

wrap around brainstem and beneath cerebral cortex

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6
Q

where is the limbic system located?

A

wrap around brainstem and beneath cerebral cortex

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7
Q

what is the limbic system the major centre for?

A

emotion formation and processing, learning and memory

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8
Q

what is the hippocampus involved in?

A

memory storage/formation, complex cognition, HPA, moderate stress

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9
Q

what structures are involved in the limbic system?

A
  • cingulate gyrus
  • parahippocampal gyrus, denate gyrus
  • hippocampus
  • amygdala
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10
Q

what is the amygdala associated with?

A

complex emotional responses esp. aggression

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11
Q

what is involved in sympathetic activation?

A
  • adrenaline and cortisol release
  • mobilise energy reserves
  • counteracts stress effects
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12
Q

what can occur if there is too much cortisol for too long?

A
  • exhaustion
  • impaired immune function
  • chronic hypertension
  • obesity
  • atherosclerosis
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13
Q

what are the basal ganglia involved in?

A

initiate and control movement

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14
Q

what are the basal ganglia involved in?

A

initiate and control movement

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15
Q

what is associated with high levels of prolonged stress?

A
  • learned anxious behaviour
  • alters neural connections
  • reduced cortical inhibition
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16
Q

what is effected when there is an imbalance of monoamines and ACh?

A

impaired…

  • motor control
  • mood
  • thought processing
17
Q

where does serotonin project from?

A

dorsal Raphe nucleus (reticular formation)

18
Q

where does noradrenaline project from?

A

Locus coeruleus (reticular formation)

19
Q

what occurs in relation to low serotonin in the prefrontal cortex?

A

difficulty seeing positive outcomes

20
Q

what occurs in relation to low serotonin in the anterior cingulate gyrus?

A

unable to shift attention

21
Q

what occurs when there is overactivity of noradrenaline?

A
  • arousal
  • stress
  • increased basal ganglia tone
  • hypertension
22
Q

what occurs when there are low levels of GABA in the anterior cingulate gyrus?

A

increased rumination

23
Q

what occurs when there are low levels of GABA in the limbic system?

A

overactivity and heightened fear response

24
Q

what occurs when there are low levels of GABA in the prefrontal cortex?

A

unable to deliberately suppress thoughts effectively, worry

25
what are types of antidepressants?
- MAOIs - tricycle antidepressants - SSRIs
26
what are types of mood stabilisers?
- lithium | - valproate
27
what are types of anxiolytics?
- benzodiazepines | - hypnotics/sedatives: zoopiclone, antihistamines, zolpidem
28
what are some pharmacological therapies for GAD?
- SSRIs - benzodizapines - SSNRIs - tricycle antidepressants and atypical SSRIs
29
what are types of antipsychotics?
- typical: flupenthixol, haloperidol | - atypical: risperidone, olanzapine
30
how do SSRIs assist with GAD?
enhance serotonin levels and improve mood
31
how do benzodiazapines assist with GAD?
inhibit limbic areas
32
how do SSNRIs assist with GAD?
enhance serotonin and noradrenaline
33
what are some other non-pharamcological therapies for GAD?
- cognitive behavioural therapy - relaxation - exercise
34
how can cognitive behavioural therapy assist with GAD?
train prefrontal cortex
35
how can relaxation assist with GAD?
reduce arousal
36
how can exercise assist with GAD?
- release endorphins - reduce circulating corticosteroid - stretch and relax muscles - decrease weight gain