stress and anxiety Flashcards

1
Q

what are different types of anxiety disorders?

A
  • seperation
  • GAD
  • specific phobia
  • agoraphobia
  • panic attack/disorder
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2
Q

what are some clinical descriptions of anxiety based on DSM-V?

A

for last 6 months…

  • worrying excessively
  • signs of physical tension
  • problems with attention/concentration
  • suffer depressed mood
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3
Q

what are some physical symptoms of GAD?

A
  • muscle tension
  • fatigue
  • edginess
  • restlessness
  • difficulty sleeping
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4
Q

what are some functions of the medial cerebral cortex?

A
  • planning
  • decision making
  • reward processing
  • predicting consequences
  • regulate impulses, emotions and behaviour
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5
Q

where is the limbic system located?

A

wrap around brainstem and beneath cerebral cortex

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6
Q

where is the limbic system located?

A

wrap around brainstem and beneath cerebral cortex

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7
Q

what is the limbic system the major centre for?

A

emotion formation and processing, learning and memory

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8
Q

what is the hippocampus involved in?

A

memory storage/formation, complex cognition, HPA, moderate stress

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9
Q

what structures are involved in the limbic system?

A
  • cingulate gyrus
  • parahippocampal gyrus, denate gyrus
  • hippocampus
  • amygdala
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10
Q

what is the amygdala associated with?

A

complex emotional responses esp. aggression

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11
Q

what is involved in sympathetic activation?

A
  • adrenaline and cortisol release
  • mobilise energy reserves
  • counteracts stress effects
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12
Q

what can occur if there is too much cortisol for too long?

A
  • exhaustion
  • impaired immune function
  • chronic hypertension
  • obesity
  • atherosclerosis
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13
Q

what are the basal ganglia involved in?

A

initiate and control movement

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14
Q

what are the basal ganglia involved in?

A

initiate and control movement

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15
Q

what is associated with high levels of prolonged stress?

A
  • learned anxious behaviour
  • alters neural connections
  • reduced cortical inhibition
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16
Q

what is effected when there is an imbalance of monoamines and ACh?

A

impaired…

  • motor control
  • mood
  • thought processing
17
Q

where does serotonin project from?

A

dorsal Raphe nucleus (reticular formation)

18
Q

where does noradrenaline project from?

A

Locus coeruleus (reticular formation)

19
Q

what occurs in relation to low serotonin in the prefrontal cortex?

A

difficulty seeing positive outcomes

20
Q

what occurs in relation to low serotonin in the anterior cingulate gyrus?

A

unable to shift attention

21
Q

what occurs when there is overactivity of noradrenaline?

A
  • arousal
  • stress
  • increased basal ganglia tone
  • hypertension
22
Q

what occurs when there are low levels of GABA in the anterior cingulate gyrus?

A

increased rumination

23
Q

what occurs when there are low levels of GABA in the limbic system?

A

overactivity and heightened fear response

24
Q

what occurs when there are low levels of GABA in the prefrontal cortex?

A

unable to deliberately suppress thoughts effectively, worry

25
Q

what are types of antidepressants?

A
  • MAOIs
  • tricycle antidepressants
  • SSRIs
26
Q

what are types of mood stabilisers?

A
  • lithium

- valproate

27
Q

what are types of anxiolytics?

A
  • benzodiazepines

- hypnotics/sedatives: zoopiclone, antihistamines, zolpidem

28
Q

what are some pharmacological therapies for GAD?

A
  • SSRIs
  • benzodizapines
  • SSNRIs
  • tricycle antidepressants and atypical SSRIs
29
Q

what are types of antipsychotics?

A
  • typical: flupenthixol, haloperidol

- atypical: risperidone, olanzapine

30
Q

how do SSRIs assist with GAD?

A

enhance serotonin levels and improve mood

31
Q

how do benzodiazapines assist with GAD?

A

inhibit limbic areas

32
Q

how do SSNRIs assist with GAD?

A

enhance serotonin and noradrenaline

33
Q

what are some other non-pharamcological therapies for GAD?

A
  • cognitive behavioural therapy
  • relaxation
  • exercise
34
Q

how can cognitive behavioural therapy assist with GAD?

A

train prefrontal cortex

35
Q

how can relaxation assist with GAD?

A

reduce arousal

36
Q

how can exercise assist with GAD?

A
  • release endorphins
  • reduce circulating corticosteroid
  • stretch and relax muscles
  • decrease weight gain