Stomach Flashcards

1
Q

history of partial gastrectomy with persistent GERD despite therapy + type 1 hiatal hernia. Best Surgical option?

A

Hill esophagogastropexy

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2
Q

What is a Dor fundoplication?

A

An ANTERIOR 180 to 200 degree fundoplication with division of the short gastric vessels via abdominal approach

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3
Q

What is a Hill esophagogastropexy?

A

Plication of the lesser gastric curvature around the right side of the esophagus with an esophagogastropexy to the median arcuate ligament.

Intraoperative manometry is required for success.

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4
Q

What procedure is commonly associated with a laparoscopic Heller esophagomyotomy for achalasia?

A

Dor fundoplication (anterior 180 to 200 degree ANTERIOR fundoplication with division of short gastric vessels

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5
Q

What is the key difference between a modified Nissen fundoplication and a traditional Nissen?

A

Division of the short gastric vessels (Not originally described)

+

circumferential 360-degree wrap of the fundus around the lower portion of the sophagus to recreate the Angle of His (original)

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6
Q

What is a Toupet fundoplication?

A

a POSTERIOR 270 degree fundoplication with division of the short gastric vessels

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7
Q

What is a Belsey Mark IV fundoplication?

Name one key distinction comparing it to other approaches.

A

an ANTERIOR 240 degree fundoplication buttressed by the diaphragmatic crura via TRANSTHORACIC APPROACH (Left posterolateral thoracotomy)

One key distinction = partial anter fundoplication is over 4cm no traditional 2cm length)

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8
Q

In GERD, what 4 risk factors are concerning for poor reponse to medical therapy?

A

1) Nocturnal reflux on 24-hour esophageal pH study
2) structurally deficient LES
3) mixed reflux of gastric and duodenal juice
4) mucosal injury at presentation

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9
Q

Parietal Cell

Which part of stomach?

Secretes?

A

Fundus and Body of stomach

Produces H+/Intrinsic Factor

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10
Q

G Cell

Which part of stomach?

Secretes?

A

Antrum

Secretes Gastrin

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11
Q

What is included in the criteria for Metabolic Syndrome?

A

waist circumference > 40 inches (men) or > 35 inches (women) PLUS at least 2 of the following:

  • SBP > 130mmHg or DBP > 85 mmHg
  • Triglyceride > 150 mg/dL
  • Decreased HDL cholesterol < 40 (men) and < 50 (women)
  • Fasting glucose > 100 mg/dL or diagnosed type 2 DM
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12
Q

What is the treatment for H. pylori?

A

PPI + clarithromycin + flagyl

Typically want PPI + 2 antibiotics (amoxicillin, clarithromycin, metranidazole, tetracycline)

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13
Q

Pneumomediastinum … what is the recommend study of choice? any particular contrast?

A

Swallow esophogram - First with gastrograffin. If no leak seen then use dilute barium.

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14
Q

Early dumping syndrome.

Symptoms?

Mechanism?

A

Symptoms: 30 minutes after eating = diaphoresis, weakness, light-headedness, tachycardia

Mechanism: hyperosmotic load being delivered ot the duodenum due to absence of a pylorus == large fluid shift

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15
Q

Late dumping syndrome.

Symptoms?

Mechanism?

A

Symptoms: 2 to 3 hours after eating w/ diaphoresis, weakness, light-headednes, tachycardia [hypoglycemic episode]

Mechanism: large insulin release due to large bolus of food hitting duodenum

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16
Q

Where is the primary location and what does of each of the following cells secrete?

Chief cells

Parietal cells

G-cells

D cells

Brunner glands

A

Chief cells: located in pepsinogen

Parietal cells

G-cells

D cells

Brunner glands

17
Q

What increases and decreases gastric acid secretion?

A

Increases in gastric acid secretion is casued by:

1) gastrin (rom antral G-cells)
2) histamine (From enterochromaffin-like cells [ECL])
3) acetylcholine (from vagal nerve input)

Gastric acid secretion is principally inhibited by somatostatin (released from D cells)

18
Q

Gastrointestinal stromal tumors (GISTs) are derived from what type of cell? Where are they found?

A
  • Derived from: Interstitial cells of Cajal (intestinal pacemaker cells)
  • Found: stomach (40-60%), small intestine (30%), and colon (15%)