Esophagus Flashcards

1
Q

Zenker Diverticulum…asymptomatic… < 1cm diverticulum…preferred treatment?

A

observation

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2
Q

Zenker Diverticulum …symptomatic … < 2cm… treatment options?

A
  • Transoral intraluminal approach
  • Diverticulopexy alone OR cricopharyngeal myotomy alone
  • Peroral endoscopic myotomy (in high volume center)
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3
Q

Zenker Diverticulum… with 2 to 5 cm diverticulum…. what are your treatment options? which one is preferred?

A
  • cricopharyngeal myotomy and diverticulopexy [preferred]

- Cricopharyngeal myotomy and diverticulectomy

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4
Q

NCCN guidelines - For esophagectomy for esophageal cancer… at least how many Lymph Nodes should you remove?

A

15 lymph nodes

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5
Q

In early stage esophageal cancer, which cancer has more early lymphatic spread - esophageal adenocarcinoma or esophageal squamous cell?

A

esophageal squamous cell

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6
Q

Barrett’s esophagus without dysplasia… endoscopic surveillance recommendation?

A

EGD every 3 to 5 YEARS with 4 quadrant biopsies taken every 2 cm along the esophagus

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7
Q

Barrett’s esophagus with dysplasia… endoscopic surveillance recommendation?

A

EGD every 3 to 6 MONTHS with 4-quadrant biopsies every 1cm along the length of the segment

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8
Q

Layers of esophagus (inside to outside)

A

mucosa
submucosa
muscularis propria
NO serosa

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9
Q

What is the esophageal blood supply (cervical vs. thoracic vs. abdominal)

A

Cervical - inferior thyroid artery
Thoracic - vessels directly off aorta
Abdominal - left gastric/Inferior phrenic arteries

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10
Q

What are the boundaries of Killian triangle?

What’s the significance of Killians triangle?

A

It is a triangular area in the wall of the pharynx:

  • Inferior border: cricopharyngeus muscles
  • Superior borders: inferior constrictor muscles

Killian triangle is a weak spot where a pharyngeoesophageal diverticulum (Zenker’s diverticulum) is more likely to occur.

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11
Q

Concern for esophageal perforation…

  • Study of choice?
  • MC site of perforation?
  • MC site of iatrogenic perforation?
A
  • Study of choice: contrast esophagography (use gastrografin [water soluble], followed by dilute barium). IF at ASPIRATION risk, use dilute barium
  • MC site of perforation - distal esophagus in left posterolateral aspect, 2-3 cm above GE junction.
  • MC iatrogenic location - cricopharyngeus
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12
Q

Treatment for esophageal perforation if its….

isolated cervical esophageal injury?

A

open neck and drain it

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13
Q

Treatment for esophageal perforation if its….
Stable patient + Thoracic perforation with leakage? [please list primary steps]

Is there anything you would do if its from achalasia?

A

Primary repair:

  • Left thoracotomy
  • Debridement of devitalized tissue
  • [MUST DO] myotomy to visualize full extent of mucosal injury
  • Repair in two layers (inner absorbable, outer permanent)
  • Cover with well vascularized tissue (intercostal/omental/latissimus flap)
  • Leak test
  • Place NGT past repair
  • Drain chest
  • Close

IF from achalasia - include CONTRALATERAL myotomy

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14
Q

Treatment for esophageal perforation if its….

unstable patient + Thoracic perforation with leakage? [please list primary steps]

A

exclusion and diversion

  • closure of perforation
  • Drainage
  • Cervical ESOPHAGOSTOMY for proximal diversion
  • T tube into defect and drain externally as controlled fistula
  • J-tube enteral access
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15
Q

Achalasia

  • Cause?
  • Manometry findings (3)?
  • Sign on imaging?
  • Treatment?
A
  • Cause: degenerative loss of nitric oxide producing inhibitory neuron w within LES (autoimmune vs. genetic vs. infectious)
  • Manometry findings: 1) high/normal LES basal pressure; 2) incomplete LES relaxation, 3) hypotonic or absent peristalsis
  • Imaging: birds beak sign on barium swallow w/ esophageal dilation
  • Tx: Heller myotomy with partial fundoplication (6cm on esophagus; 2cm onto stomach)
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16
Q

What is pseudoachalasia?

A

Achalasia caused by malignancy

17
Q

Organism causing Chagas disease that can lead to achalasia?

A

Trypanosoma cruzi

18
Q

What is the manometry findings for isolated hypertensive LES?

Treatment?

A

Manometry findings:

  • HIGH Basal LES pressure
  • Complete LES relaxation
  • Normal Peristaslsis

Treatment: Calcium channel blockers, nitrates, Heller myotomy

19
Q

What is the manometry findings for diffuse esophageal spasm?

Treatment?

A

Manometry findings:

  • Normal LES pressure
  • Normal LES relaxation
  • High amplitude, uncoordinated esophageal contractions (30>mmHg simultaneous contractions in >10% of swallows)

Treatment: Calcium channel blockers, nitrates. Surgery less effective (needs long segment myotomy in extreme cases)

20
Q

What is the manometry findings for nutcracker esophagus?

Treatment?

A
  • Normal LES pressure
  • Normal relaxation
  • High amplitude, coordinated esophageal contractions

Tx: calcium channel blockers, nitrates. Surgery less effective (needs long segment myotomy in extreme cases).

21
Q

Epiphrenic esophageal diverticula

  • Type of diverticulum?
  • Associated with?
  • Treatment?
A
  • Type: pulsion diverticulum
  • Associated with: esophageal motility disorders
  • Tx: Diverticulectomy and treatment of underlying motility disorder (may meed heller myotomy)
22
Q

Thoracic/Mid-esophageal diverticula

  • Type of diverticulum?
  • Often seen with what diseases?
  • When and what treatment?
A
  • Type: Traction diverticulum (a TRUE)
  • Seen with inflammatory diseases (TB, malignancy)
  • Treatment if symptomatic: VATS diverticulectomy and myotomy
23
Q

Define Barrett’s esophagus.

What cancer are you at increased risk of getting and how increased is your risk?

A

Intestinal metaplasia of the lower esophagus from squamous cell to columnar cells

30-60x increased risk for esophageal ADENOCARCINOMA

24
Q

Barrett’s esophagus with high grade dysplasia on biopsy.

Next step?

A

repeat biopsy. Confirm with experg GI pathologist.

ENDOSCOPIC MUCOSAL RESECTION if high grade dysplasia confirmed.

25
Q

TNM for Esophageal cancer?

Where are the important clinical distinctions?

A

T1a- invades lamina propria/muscularis mucosa
T1b - invades submucosa***
T2 - invades muscularis propria
T3 - invades adventitia
T4a - invades resectable surrounding structures (pleura/pericardium diaphragm)
T4b - invades unresectable surrounding structures (aorta, vertebrae, trachea)

N1: 1-2 nodes
N2: 3-6 nodes
N3: 7+ nodes

M1: +distant mets