STIs Flashcards
Chancroid
Haemophilus ducreyi G-ve
Painful superficial ulcer/s
LNpathy -> buboe
Abx: erythromycin
Chlamydia
Chlamydia trachomatis serovars D-K
Female: asymptomatic/discharge, dysuria, frequency
-> PID, peri hepatitis F-H-C synd = RUQ pain -> infertility
Male: mucopurulent discharge, dysuria
-> epididymorchitis
Ix: urine antigen detection/swab culture
Rx: doxycycline
Trichomoniasis
Trichomonas vaginalis =flagellated protozoan
Grey/green discharge, dyspareunia, dysuria, vaginitis, strawberry cervix (punctate erythema)
Men usually asymptomatic
Invades superficial epithelial cells
Ix: microscopy/culture
Rx: metronidazole
Gonorrhoea
Neisseria gonorrhoea G-ve diplococcus
Infects GU tract, rectal + pharyngeal mucosa
Women asymptomatic
Complications: bartholin’s, salpingitis
Men after 3-5 days dysuria, freq, discharge, urethritis, meatal oedema
Disseminated infection: pyrexia, polyarthritis, vasculitis rash,
Primary Syphillis
Treponema pallidum
10-90 days post infection, dull red papule, single painless well demarcated ulcer = chancre, heals within 8 wks
Dark field microscopy from serum at base of chancre / direct immunofluorescence/ serology
Rx: penicillin
Lymphogranuloma venereum
Chlamydia trachomatis serovars L1-3
Painless papule at 3-21 days, ulcerated and heals within days
Unilateral lymphadenopathy -> inguinal buboes, sinus develops
Acute ulcerative proctitis may occur if rectal mucosa infected
Diagnosis on culture or serology
Rx: tetracycline
Grnauloma inguinale aka Donovanosis
Tropical condition, Klebsiella granulomatis
Flat topped papule, ulcerated and spreads along skin folds, heals with scarring eventually
Giemsa stained smear microscopy: Donovan bodies in mononuclear cells
Rx: tetracyclines or co-trimoxazole
HSV
Dysuria, painful + itchy lesions
Vesicular, pustular lesions, crust and heal within 4 wks
Remains dormant in dorsal root ganglion, deactivation in 75%
Recurrent attacks usually milder and shorter
Diagnosis by viral swabs
Rx: oral acyclovir
