Drugs In Pregnancy Flashcards

1
Q

Mat hyperthyroidism

A

90% secondary to Graves
Propylthiouracil> carbimazole
Lowest dose required to keep free thyroxine at upper limit of normal
(Reduce fetal hypothyroidism as a side effect)
Euthyroid for 4 weeks -> stop medication under close monitoring

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2
Q

Hyperemesis gravidarium

A
Oral antiemetics: promethazine 
Dehydration/significant ketonuria = admit
IV fluids, NBM
Metoclopromide, ondansetron 
Thiamine supplements
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3
Q

Obstetric cholestasis

A

Chlorphenamine- for pruritus
Oral vit K supplements
Ursodeoxycholic acid - reduce bile salt accumulation

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4
Q

PID

A

Doxycycline CI
Tetracyclines deposit in teeth and bones, delaying growth
If breastfeeding stains baby’s teeth
Alt = macrolide erythromycin, treatment of choice for PROM

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5
Q

Analgesia

A

1st line paracetamol
2nd line diclofenac

CI in pregnancy and when breast feeding: opiates e.g. Codeine

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6
Q

CI

A
Acitretin
Methotrexate 
Me bendable
Fluconazole
Quinolones: ciprofloxacin
Tetracyclines: doxycycline
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7
Q

Relative CI

A

Sodium valproate

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