STIs Flashcards
What is syphilis caused by?
- Treponema pallidum (Spirochete)
What is the clinical presentation of syphilis?
- Appearance of a chancre
How long does primary, secondary, latent, and tertiary syphilis last for?
P: (1-3weeks) chancre
S: (6-12weeks) fever, lymphadenopathy, rash
L: (1-10 years) “hidden” stage
T: (10-30 years) damage to internal organs=death
What is the treatment of primary, secondary, early latent syphilis?
- Benezathine Penicillin G 2.4 million units IM X 1 dose
What is the treatment for late latent syphilis?
- Benzathine pencillin G 2.4 million units IM X 3 doses at weekly intervals
What causes gonorrhea?
Neisseria gonorrhoeae
*gram negative
What is the treatment for gonorrhea?
- Ceftriaxone 500 mg IM X 1 dose
AND - Doxycycline 100mg PO BID X 7 days (if chlamydia is not excluded)
*this is weight based
*>150kg use 1000mg Ceftriaxone
What causes chlamydia?
- Chlamydia trachomatis
What is the treatment for chlamydia?
- Doxycycline 100mg by mouth BID X 7 days
What is Trichomoniasis caused by?
- Protozoan parasite Trichomonas vaginalsis
What is the treatment for men and women for trichomoniasis
W: metronidazole 500 mg PO BID X 7 days
M: Metronidazole 2g PO X 1 dose
What causes herpes?
Herpes simplex virus
1. HSV-1 (oral)
2. HSV-2 (genital)
What is the treatment of herpes for the first episode?
Antivirals
1. Acyclovir 400mg by mouth TID 7-10 days
OR
2. Valacyclovir 1g PO BID/ 7-10 days
What is the treatment of herpes for recurrent infections?
- Acyclovir 800mg BID or TID/ 5 days
- Valacyclovir 1g PO QD/ 5 days
What is the treatment of herpes for suppressive therapy?
- Acyclovir 400mg BID
- Valacyclovir 500mg/1g QD