Pain Management Flashcards

1
Q

What are the 3 main areas within accrediting standards when evaluating pain

A
  1. Assessment and management of acute pain
  2. Assessment and management of chronic pain
  3. Recognition, management, and/or referral of patients addicted to opioids
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2
Q

What is break-through-pain

A
  1. Sharp spikes of severe pain despite use of ER opioid
    *must treat with fast acting agent
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3
Q

What are the broad efficacy outcomes

A
  1. Pain relief
  2. Change in pain
  3. Pain intensity
  4. adequate functionality
  5. Duration of action
  6. Route of adminsitration
  7. QOL
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4
Q

What are the safety outcomes

A
  1. Side effects
  2. Route of adminsitration
  3. QOL
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5
Q

What are the five A

A
  1. Analgesia
  2. Activities of daily living
  3. Aberrant drug behavior
  4. Adverse effects
  5. Affect
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6
Q

What to consider when selecting a pharmacological agent

A
  1. Select the simplest approach possible
  2. When starting for chronic pain use IR release at lowest effective dose (avoid LA/RA)
  3. Use the lowest effective IR dose for acute pain
    *3 days typically enough
  4. Avoid placebos
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7
Q

What does “By the clock, by the mouth, by the ladder” mean

A

When the schedule pain medications
*PO
*ladder = mild pain 1-3, moderate 4-7, severe pain 7-10

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8
Q

What are the medication for mild pain (1-3) and moderate pain (4-6)

A

Nonopioid adjuvant
1. Codeine
2. NSAIDS/APAP/ASA
Opioid for mild to moderate pain (can also be used for severe)
1. Hydrocodone
2. Oxycodone
3. Pentazocine
4. Butorphanol
5. Nalbuphine
6. Buprenorphine

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9
Q

What are the medications to use for severe pain (7-10)

A

DOC = morphine
1. Fentanyl (for quick on and off)
2. Hydromorphone
3. Oxymorphone
Severe chronic = methadone

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10
Q

How to pick the correct medication for pain

A
  1. What is the patients pain level
  2. Base the pick off of the pain ladder
    *choose one that can provide adequate analgesia
  3. What interventions are planned for the patient
  4. What medication has the best pharmacokinetic profile for the patient
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11
Q

What are the acute pain management principles

A
  1. Begin at typical starting dose
  2. Continue analgesics around the clock
    *PRN opioids for breakthrough pain (always have BTP option)
  3. Reserve IV infusion for opioid tolerant patients
  4. Include APAP and NSAIDs in pain management unless CI
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12
Q

What pain meds are used in the ED for severe or localized pain

A

Severe
1. IV opioids (fentanyl, morphine)
2. Ketamine (IV, IM, IN)
3. Ketorolac IV
Localized pain
1. Local anesthetic for painful local injuries
2. Regional blocks

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13
Q

What pain meds are used in the ED for breakthrough pain, and other options

A

Breakthrough pain
1. Oral opioids (Oxycodone, hydrocodone, tramadol)
Unless CI
1. NSAIDS
2. Acetaminophen

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14
Q

What is the acute treatment for musculoskeletal pain

A
  1. Multimodal analgesia, NSAID, APAP
  2. Use lowest effective IR opioid for shortest duration
  3. No ER opioids
  4. Consider local/regional block anesthesia
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15
Q

What are the clinical pearls of treating a musculoskeletal injury

A
  1. Opioids are ineffective and NOT recommended for chronic mechanical low back pain
  2. Opioids should be limited and restricted to only a short duration for low back pain
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16
Q

What is the first line tx and opioid therapy for chronic pain

A

First line
1. Nonpharmacolgic and nonopioid pharmacolgic therapy
Opioid therapy
1. Use nonpharmacologic therapy and non opioid pharmacological therapy

17
Q

What should you avoid for chronic pain

A
  1. Benzodiazepines
18
Q

How to choose the best medication

A
  1. Opioids are last resort, timed limited trial
  2. Balance the potential risk/benefits with attention to risk factors for misuse and abuse
    *substance abuse disorder
19
Q

How to minimize risk for people with chronic pain

A
  1. Avoid opioid pain medication and benzodiazepines together whenever possible
  2. Offer medication assisted treatment with buprenorphine or methadone
20
Q

How to appropriately follow up and discontinue meds

A
  1. Reassess benefits and risk when increasing dosage to >50MME/day
    *avoid increases to >90MME/day
  2. Re-evaluate within 1-4 weeks for starting or increasing
  3. Re-evaluate at minimum every 3 months
21
Q

When should you consider tapering an opioid?

A

When your patient
1. Request it
2. Does not have improvement in pain at least 30% improvement
3. On dosages >50MME/day
4. Shows signs of substance use disorder
5. Shows early warning signs for overdose risks such as confusion, sedation, or slurred speech

22
Q

How to taper an opioid

A
  1. Go slow
  2. 10% decrease per month, if taking opioid >1year
    *10% per week may work for those who have only taken for weeks to months
  3. Lowest dose then extend the interval between doses (stop when taken <1x/day)
23
Q

In chronic pain management, at WHAT total morphine milligram equivalent per day do the risk of therapy start to outweigh potential pain control benefits?

A

50 MME/day

24
Q

What is the problem with high dose opioids

A

Higher dosage = higher risk of overdose and death
1. Doses at or above 50MME/day at least double the risks for overdose
2. Dose base on IBW (ideal body weight)

25
Q

What are the opioid cross-sensitivities

A

Phenanthrenes (morphine-like)
*morphine
*codeine
*oxycodone
Phenylpiperidines (meperidine-like)
*meperidine
*fentanyl

**risk of cross-sensitivity in patients with allergies is greater when medications are form the same family

26
Q

How to calculate TDD

A
  1. Determine the total daily amount of each opioid being taken
  2. Convert each total daily amount of each opioid to MME
    *multiple by conversion factor
  3. Add all opioid together to get the total daily dose
27
Q

What should you not use to calculate the MME

A
  1. Do not use the RAW calculated MMEs to determine dosage when converting one opioid to another
28
Q

What is the first line treatment for neuropathic pain

A
  1. TCA
  2. SNRIs
    *duloxetine / venlafaxine
  3. Gabapentanoids
  4. Topical
    *2 and 3 preferred
29
Q

What is the second line treatment for neuropathic pain

A
  1. Tramadol
  2. Combination (gabapentanoid + either TCA or SNRI)
30
Q

What is a key side effect of Neurontin that may lead to it’s discontinuation by a patient despite it’s positive effects on neuropathic pain?

A

Weight gain