Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Microbiology > Sthapylococcus > Flashcards

Sthapylococcus Flashcards

1
Q

Sthapylococcus Grow in media containing

A

10% NaCl at temp 18 to 40 C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Staphylococcus Present on the

A

skin and mucus membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Staphylococcus Resistant to

A

drying and heat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Slime layer or capsule

What kind of layer

A

Polysaccharide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Slime layer or capsule

Protects bacteria

A

Inhibition of chemotaxis and phagocytosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Slime layer or capsule

Facilitate adherence to

A

Catheters and synthetic materials

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Slime layer or capsule

Covalently linked to

A

Peptidoglycans

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Slime layer or capsule

Has affinity to

A

FC receptor of IG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Slime layer or capsule

Blocks

A

Opsonization and phagocytosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Ribitol teichoic acid with N-acetylglucosamine (Polysaccharide A)

A

S. aureus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Glycerol teichoic acid with glucosyl residues (polysaccharide B)-

A

S. epidermidis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Disrupts smooth muscle in the blood vessel
Toxic to RBC, platelets, hepatocytes
Cause cell lysis-efflux of K, influx Na, Ca- osmosis
Septic shock

A

Alpha

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Damage membrane of susceptible cells
Lyze neutrophils and macrophage
Cell lysis
Necrotizing skin infection

A

Gamma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Disrupts cell membrane

Toxic to variety of cells

A

Delta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Specific for sphingomyelin and lysophosphatidylcholine
Toxic to RBC, WBC, macrophage ,fibroblast
Tissue destruction and abscess formation

A

Beta

Sphingomyelinase C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Kills WBC, leucotoxic

A

Phanton valentine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Exfoliative toxin

Heat stable

A

ETA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Exfoliative toxin

Heat Labile

A

ETB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Exposure of exfoliative toxin

A

splitting of desmosomes or intercellular bridges in the stratum granulosum epidermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Exfoliative toxin common in neonates. ETA and EBA binds to

A

GM4 like glycolipids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Entertoxin

A

A-E

G-I

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Entertoxin are

A

Stable to heating

Resistant to hydrolysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

o – most commonly associated with disease

A

Enterotoxin A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q
  • contaminated milk products
A

oEnterotoxin C and D

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q
  • Pseudomembranous colitis
A

oEnterotoxin B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

TSST -1

Formerly pyrogenic

A

Exotoxin C

Entertoxin F

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

TSST -1

Induce cytokine release from

A

Macrophage and T cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

TSST -1

Increase sensitivity to

A

Endotoxin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

TSST -1

Produce leakage of

A

Endothelial cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

TSST -1

Penetrate

A

Mucosal barrier

31
Q

Enzymes

Fee and bound

32
Q

Enzymes

Coagulate convert fibrinogen to

A

Insoluble fibrin to staphylothrombin

33
Q

Enzymes

Cause formation of fibrin around abscess protecting organism from phagocytosis

A

Clumping factor

34
Q

Enzymes

Catalyze the conversion of toxic hydrogen peroxide to water and oxygen

35
Q

hydrolyzes hyaluronic acid in acellular matrix of connective tissue to spread

A

Hyaluronidase

36
Q

.

•Dissolve fibrin clot- aid in bacterial spreading

A

oFibrinolysin- staphylokinase

37
Q

hydrolyse lipid to ensure survival in sebaceous areas of the body

38
Q

oPenicillinase

•

39
Q
  • antibacterial lipid- prolonged bacterial survival
A

oFatty acid modifying enzyme (FAME)

40
Q

Epidemiology

A

Transient colonizer of skin

41
Q

Epidemiology

Nasal carrier

A

Anterior nasopharynx

42
Q

Epidemiology

Persistent carrier

A

Hospital personnel

43
Q

Ritters Disease or SSSS

Pathophysiology

A 
Perioral erythema to
Spread to
Body to
Bullous to
Desquamation
44
Q

Ritters Disease or SSSS

Sign

A

Nikolsky sign

45
Q

Ritters Disease or SSSS

Localized from of SSSS

A

Bulbous impetigo

46
Q

Ritters Disease or SSSS

Bullous impetigo

A

Localized blister

Culture positive

47
Q

TSS

Growth of organism in vagina or wound

A

Release of TSST -1

48
Q

TSS

Manifestations

A 
Fever
Macular erythematous
Hypotension
Multi organ involvement
Desquamtion of Palm and sole
49
Q

Cutaneous infection

A 
Impetigo
Folliculitis
Furuncle
Carbuncle
Wound infection
50
Q

Others

A 
oBacteremia
oEndocarditis
oPneumonia
oEmpyema
oOsteomyelitis
oSeptic arthritis
51
Q

S. Aureus is positive from

A

Alpha toxin (most strains)
Acid from mannitol
Coagulase reaction
DNase production (usually)

52
Q

S aureus pigment production

A

Usually golden

53
Q

S epidermis pigment production

54
Q

S. Saprophiticus

55
Q

S. Epidermidis and CNS

A

oEndocarditis- native or artificial valves
oCatheter and shunt infection
oProsthetic joint infection
oUTI

56
Q

Laboratory diagnosis

Grow rapidly within

57
Q

Laboratory diagnosis

Blood agar

58
Q

Laboratory diagnosis

Selective media

A

Add NaCL 7.5%

59
Q

Laboratory diagnosis

Mannitol

A

Fermented by S. Aureus

60
Q

Laboratory diagnosis

Catalase test

A

3% H2O2 bubbles

61
Q

Treatment

Semisynthetic penicillinase resistant penicillin

A

oOxacillin/Cloxacillin
oNafcillin
oClindamycin
o1st Gen cephalosporins

62
Q

Resistance

MSSA gene

63
Q

Resistance gene

MRSA

A

Me gene

SCCmec

64
Q

Resistance gene

VISA

65
Q

Resistance gene

VRSA

66
Q

Resistance comment

MSSA

67
Q

Resistance comment

MRSA

A

Vancomycin sensitive

MIC 2

68
Q

Resistance comment

VISA

A

Quinopristine dalfopristine
oxazolidinone

MIC > 4-8

69
Q

Resistance comment

VRSA

70
Q

Resistance

Betalactamase

A

Penicillin

71
Q

Plasmid mediated

A

Tetracycline
Erythromycin
Aminoglycosides

72
Q

Tolerance

A

Inhibit growth

Not killed

73
Q

Staphylococcus

A

oNon motile, non sporeformer
oAerobic or Facultative Anaerobic
oFerment CHO to lactate
oCatalase positive

Microbiology (6 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions