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Microbiology > Staphlococcus Summary > Flashcards

Staphlococcus Summary Flashcards

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1
Q

Cell wall components

Peptidoglycans

A 
Hydrolyze by lysozyme
Endotoxin like property
Macrophage
Cytokines
Component cascade
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2
Q

Cell wall components

Protein A

A

IgG 1,2&4
Reduced C3B
Reduced opsonization
Reduced phagocytosis

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3
Q

Cell wall components

Teichoic acid

A

Ribitol phosphate
Mucosa receptors
Septic shock

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4
Q

Virulence Factors

Cytolysis or hemolysis

A

Affected RBC and Leukocytes

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5
Q

Virulence Factors

Alpha

A

Severe tissue damage
Septic shock
Damage RBC, Platelets and macrophage

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6
Q

Virulence Factors

Beta

A

Sphingomyelin

Lysophospatidyl choline

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7
Q

Virulence Factors

Delta

A

Less toxic than alpha and beta

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8
Q

Virulence Factors

Gamma

A

PVL related
Cell lysis
Invasiveness
Inhibit phagocytosis

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9
Q

Virulence Factors

Exfoliative toxin

A 
Group 2
SSSS 
Ritter disease
Bullous impetigo
Basta stratum granulosum ang affected
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10
Q

Virulence Factors

Toxic shock syndrome toxin 1

A 
TSST 1
Exotocin C
Entertoxin F
Super antigen 
Basta endothelial cells and chromosome
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11
Q

Virulence Factors

Entero toxins A-E and G-J

A 
Group 3
Super antigen din
Peristalsis
Food poisoning (ABD)
TSS (BDGI)
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12
Q

Enzymes

Coagulase

A 
Aureus
CoNs
Marker for virulence
Fibrinogen to fibrin
Clumping factor
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13
Q

Enzymes

Catalase

A

All staph

Hydrogen to water and oxygen

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14
Q

Enzymes

Penicillinase

A

Plasmid

Beta lactam ring

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15
Q

Enzymes

Hyaluronidase

A

Spread of organism

Intracellular ground

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16
Q

Enzymes

Slime productions

A

Some Cons
PolysacchRide adherent
Inhibit chemotaxis and phagocytosis

17
Q

Epidemiology

A

Normal skin - epidermidis
Transient skin - aureus
Colonization - aureus

18
Q

Neonates

A

Umbilicus
Skin
Perineum

19
Q

Older children

A

Anterior nasopharynx

20
Q

Clinical syndrome associated with S. Aureus

SSSS
Culture

A

4+ nasopharynx

1+ skin and blood

21
Q

Clinical syndrome associated with S. Aureus

TSS

A

Menstruating women using tampons
Multiple organ system involvement
4+ vagina
1+ blood and skin

22
Q

Clinical syndrome associated with S. Aureus

Food poisoning

A

4-24 hours

Culture 4+ food and 1+ feces

23
Q

Clinical syndrome associated with cons

A

Artificial valves
Shunt infections
Prosthetic joints
UTI sexually active women ( Saprophyticus)

24
Q

Treatment

Beta lactamase production

A

Oxacillin
Cloxacillin
Nafcillin
Methicillin

25
Q

If methicillin resistant due to PBP alteration

A

Vancomycin

Teicoplanin

26
Q

Cell wall components

Capsule

A

Polysaccharides

Inhibit phagocytosis

Microbiology (6 decks)

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