Staphylococcus Manual Flashcards
General caharacteristic of staphy
Grape like cocci Non mobile Non spore forming Catalase Normal grow skin or mucosa
Biochemical properties
Aureus
Mannitol and glucose
Biochemical properties
Epidermidis
Glucose only
Biochemical properties
Saprophyticus
Doesn’t ferment mannitol or glucose
Both susceptible to novobiocin
Aureus and epidermidis
Cell wall component
Capsule
Polysaccharide
Inhibits phagocytosis
Cell wall component
With endotoxin like property
Stimulate macrophage to produce cytokines and activate complement cascade
Cell wall component
Peptide linked glycan chains
Hydrolize by lysozyme
Provide osmotic stability
Peptidoglycans
Cell wall component
Covalently linked to glycan layer
Protein A
Cell wall component
Protein A binds Fc region of
IgG1 IgG2 IgG4 Reduce C3b Reduced opsonization Reduced phagocytosis
Cell wall component
Polymers of rib it’ll phosphate
Teichoic acid
Cell wall component
Attack to mucosa surface receptors
Teichoic acid
Cell wall component
Teichoic acid play a role in induction of
Septic shock
3 species
Aureus
Epidermidis
Saprophyticus
