Steroids Flashcards
0
Q
steroid effects on carbs, proteins, and fats (3)
A
increases circulating levels of glucose, FFA, and amino acids
antagonizes insulin
redistribution of body fat
1
Q
Hydrocortisone (Cortef) properties
A
equal mineralocorticoid and glucocorticoid properties
2
Q
steroid CV effects (4)
A
increase vascular responsiveness to sympathetic stimulation
increased catecholamine effect
increased CV output (preload and stroke vol)
some Na+ and H2O retention (volume increase)
3
Q
steroid effects of endocrine (2)
A
decrease ACTH, GH, TSH, LH increase PTH (osteoporosis) and epinephrine
4
Q
steroid immune effects (3)
A
immunosuppressive
blocks all steps in inflammation
suppression of wound healing
5
Q
glucocorticoid antagonist
A
Mifepristone (RU 486)
6
Q
mineralocorticoid antagonist
A
spironolactone
7
Q
corticosteroid synthesis inhibitors (2)
A
Aminoglutethimide
Ketoconazole
