Cholinergic Agents Flashcards
cevimeline (type)
muscarinic receptor agonist
selective for M3
pilocarpine (type)
muscarinic receptor agonist
pilocarpine use
glaucoma
methacholine type & side effect
muscarinic receptor agonist
bronchoconstriction
bethanechol type & side effect
muscarinic receptor agonist
urination
arecoline type & side effect
muscarinic receptor agonist
excessive sweating
muscarinic receptor agonist side effects (5)
sweating GI motility miosis increased saliva bronchoconstriction
varenicline type
partial nicotinic agonist
nicotinic agonist toxicity treatment
atropine
indirect cholinergic agonist mechanism of action
increased ACh time in the synaptic cleft
neostigmine type & use
cholinesterase inhibitor
myasthenia gravis tx
physostigmine type, treatment, and special characteristic
cholinesterase inhibitor
glaucoma tx
enters the CNS
edrophonium type & use
cholinesterase inhibitor
diagnosis of myasthenia gravis
organophosphate drugs
cholinesterase inhibitor, irreversible
Atropine drug type, use, characteristic
antimuscarinic
used in MI to decrease bradycardia
oral, enters CNS
atropine contraindications
glaucoma
BPH
scopalomine drug type, use, characteristic
antimuscarinic
motion sickness, pre-anesthetic
enters CNS
glycopyrrolate type and use
antimuscarinic
prevent vagal reflexes in surgery
tropicamide type & use
antimuscarinic
induction of short-acting mydriasis
homatropine type & effect
antimuscarinic
mydriasis
ipratropium & tiotropium type, effect, and use
antimuscarinic
bronchodilation
asthma
tolterodine, fesoterodine, darifenacin, solifenacin
type, special characteristic, & use
antimuscarinic
selective for M3
tx overactive bladder
oxybutynin & trospium type & use
antimuscarinic
tx bladder spasm after prostate surgery
antimuscarinic effects
dry mouth, decreased sweating, increased HR, blurred vision, mydriasis, urinary retention, hot/dry skin, bronchodilation, decreased GI motility
muscarinic antagonist contraindications (2)
narrow angle glaucoma
BPH
tx for muscarinic antagonist toxicity
cholinesterase inhibitor
antimuscarinic, selective for M3 (4)
tolterodine
fesoterodine
darifenacin
solifenacin
antimuscarinics used to induce mydriasis (2)
tropicamide
homatropine
succinylcholine contraindications
soft tissue injury (burns, rhabdo, muscular dystrophy)
children under 8
succinylcholine type
depolarizing muscular blocker
tubocurarine type
non-depolarizing neuromuscular blocker
hexamethonium type
ganglion receptor blockers
mecamylamine type & characteristic
ganglion receptor blocker
enters CNS
ganglion receptor blocker effects (4)
mydriasis/loss of accommodation
orthostatic hypotension
tachycardia
urinary retention
