Starling Forces

Question 1

Fluid exchange bw plasma and interstitium

Answer 1

Occurs across walls of systemic capillaries
Bi-directional
Determined via starling forces

Question 2

Starling forces sum

Jv
Kf

Answer 2

Jv= Kf ((Pc-Pi)-(Oc-Oi))

Jv= fluid flux across capillary wall
Kf= filtration coefficient= hydraulic H2O permeability (Lp)x Capillary SA (A)

Question 3

Pc
Pi

Oc
Oi

Answer 3

Pc= HP of cap, drives fluid into interstitium
Pi- HP of interstitium, opposes flow into interstitium

Oc= OP of cap, opposes fluid efflux from cap
Oi= OP of interstitium, pulls fluid into interstitium

Question 4

Arterial vs Venous end

Answer 4

A= favors filtration from capillary to interstitium

V- favors uptake to capillary

Question 5

Edema

Localized edema

Answer 5

Abnormal expansion of interstitial fluid compartment

Venous obstruction- inc Pc
Inflammation- inc Pc and Kf
Lymphatic obstruction= inc Oi

Question 6

Generalized edema

Answer 6

Na retention and expansion of entire ECF

Renal, Cardiac, Hepatic failure