Nephrotic case studies Flashcards
1
Q
AL Amyloidosis and Light chain
A
PC production of Ig light chains- lambda/kapp is diagnostic
2
Q
Most common cause of death in Amyloidosis
A
Pulmonary edema with cardiac invovlement (CHF or arrythmia usually)
3
Q
First step in DN
A
Measure urine protein/creatinine to determine proteinuria
4
Q
ACEI or ARB for proteinuria & HTN
A
Antiproteinuric agents
reduce GC Pressure, decreasing permeability
Reduce TGFB production, and therefore fibrosis
5
Q
Coarse loop granular staining for IgG and C3
Fine loop granular staining for IgG and C3
A
APSGN
MN
6
Q
Hypercoagulability due to
A
loss of AT3
platelet aggregation
hemoconcentration