Nephrotic case studies Flashcards

1
Q

AL Amyloidosis and Light chain

A

PC production of Ig light chains- lambda/kapp is diagnostic

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2
Q

Most common cause of death in Amyloidosis

A

Pulmonary edema with cardiac invovlement (CHF or arrythmia usually)

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3
Q

First step in DN

A

Measure urine protein/creatinine to determine proteinuria

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4
Q

ACEI or ARB for proteinuria & HTN

A

Antiproteinuric agents
reduce GC Pressure, decreasing permeability
Reduce TGFB production, and therefore fibrosis

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5
Q

Coarse loop granular staining for IgG and C3

Fine loop granular staining for IgG and C3

A

APSGN

MN

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6
Q

Hypercoagulability due to

A

loss of AT3
platelet aggregation
hemoconcentration

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