Staphylococcus aureus

Question 1

What is epyema

Answer 1

Collection of pus mostly in the pleural cavity

Question 2

Virulence factors of staphylococcus

Answer 2

Peptidoglycan
Capsule
Slime layer
Teichoic acid 
Protein 
Coagulate

Question 3

What is nosocomial

Answer 3

Disease caused and originated from hospital

Question 4

what does techoic acid do

Answer 4

binds to fibronectin

Question 5

what does protein a do?

Answer 5

virulence factor of staphylococcus binding protein. binds opzonization

Question 6

what does coagulase do?

Answer 6

(staph) converts fibrogin to fibrin

Question 7

What virulence factors does stahylococcus aureus uses?

Answer 7

capsule (protect from phagocytosis)
slime layer (binds bacteria to foreign body)
Protein A (binds opzonization)

Question 8

what is cytotoxin

Answer 8

death or toxic of many cells (blood cells)

Question 9

what is a super antigen?

Answer 9

stimulates proliferation of T cells & release cytokines

stimulates release of inflammatory mediators in mast cells (increase intestinal peristalsis & fluid loss; vomit)

Question 10

Toxic shock syndrome

Answer 10

superantigen, produce leakage or cellular destrcution

Question 11

What causes Staphylococcus food poisoning and what are the symptoms?

Answer 11

caused by bacterial toxin; diarrhea, fluidloss, vomit

Question 12

What is impetigo?

Answer 12

localized cutaneous infection, pus filled vesicle

Question 13

what is folliculitis?

Answer 13

impetigo of hair follicle

Question 14

what is bacteremia?

Answer 14

spread of bacteria into the blood, can cause endocarditis

Question 15

what is pneumonia?

Answer 15

infection of the lungs

Question 16

what is furuncles?

Answer 16

boils, extension of folliculitis, large painful nodules

Question 17

What is MRSA?

Answer 17

methicillin resistant staphylococcus aureus

known for producing serious infection

Question 18

where is MRSA normally found?

Answer 18

human skin, mucosal surfaces

Question 19

MRSA risk factors

Answer 19

presence of foreign body
surgical procedure
use of antibiotic that suppress normal microbial flora

Question 20

What kind of infection does Staphylococcus aureus cause?

Answer 20

community acquired skin and soft tissue infection

Question 21

what are toxin mediated disease by staph aureus

Answer 21

scalded skin syndrome (disseminate epithelial cells of infants)
food poisoning food (contaminated with heat stable enterotoxin)
toxic shock (multisystem intoxication chrarcter)