Staphylococcus aureus Flashcards
What is epyema
Collection of pus mostly in the pleural cavity
Virulence factors of staphylococcus
Peptidoglycan Capsule Slime layer Teichoic acid Protein Coagulate
What is nosocomial
Disease caused and originated from hospital
what does techoic acid do
binds to fibronectin
what does protein a do?
virulence factor of staphylococcus binding protein. binds opzonization
what does coagulase do?
(staph) converts fibrogin to fibrin
What virulence factors does stahylococcus aureus uses?
capsule (protect from phagocytosis) slime layer (binds bacteria to foreign body) Protein A (binds opzonization)
what is cytotoxin
death or toxic of many cells (blood cells)
what is a super antigen?
stimulates proliferation of T cells & release cytokines
stimulates release of inflammatory mediators in mast cells (increase intestinal peristalsis & fluid loss; vomit)
Toxic shock syndrome
superantigen, produce leakage or cellular destrcution
What causes Staphylococcus food poisoning and what are the symptoms?
caused by bacterial toxin; diarrhea, fluidloss, vomit
What is impetigo?
localized cutaneous infection, pus filled vesicle
what is folliculitis?
impetigo of hair follicle
what is bacteremia?
spread of bacteria into the blood, can cause endocarditis
what is pneumonia?
infection of the lungs
what is furuncles?
boils, extension of folliculitis, large painful nodules
What is MRSA?
methicillin resistant staphylococcus aureus
known for producing serious infection
where is MRSA normally found?
human skin, mucosal surfaces
MRSA risk factors
presence of foreign body
surgical procedure
use of antibiotic that suppress normal microbial flora
What kind of infection does Staphylococcus aureus cause?
community acquired skin and soft tissue infection
what are toxin mediated disease by staph aureus
scalded skin syndrome (disseminate epithelial cells of infants)
food poisoning food (contaminated with heat stable enterotoxin)
toxic shock (multisystem intoxication chrarcter)
