Neisseria Flashcards

1
Q

LOS

A

lipooligosaccharide has endotoxin activity
lipid A, core oligosaccharide
NO O-ANITGEN polysaccharide

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2
Q

LPS

A

lipopolysacchardie has O-antigen polysacchardide

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3
Q

virulence factor and function of Neisseria gonorrhoeae

A
  1. pilin- initial attachment to human cell
  2. pore protein- prevent phygolysosome in neutrophils
  3. opa protein - mediate film attachment to eukaryotic cell
  4. rmp protein- protects suface antigen from anitbodies
  5. Transferrin, Lactoferrin, hemoglobin binding protein- mediate iron to metabolism
  6. lipooligosacchardie- endotoxin activity
  7. IgA I protease- detroys immunoglobin A1
  8. B lactomase- hydolyses b lactamin ring
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4
Q

how is neisseria gonorrhea trasnmitted

A

sexual contact

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5
Q

gonorrhea infection in men

A

acute urethritis

purulent discharge

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6
Q

gonorrhea infection in women

A

endocervix
cervical disharge, abdominap pain
pelvic inflammatory disease- ectopic preg , sterile

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7
Q

gonorrhea oral infection

A

acquire during vaginal birth

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8
Q

resoior of gonorrhea

A

human

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9
Q

what increases the rsk of gonorrhea

A

multiple sex partners

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10
Q

what does neisseria meningitidis cause

A

meningitis

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11
Q

outer surface that N meningitidis have

A
  1. capsule
  2. pili
  3. lipooligosaccharide
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12
Q

n meningitidis resorvoi and how it spreada

A

humans, person to person, resp tract secretion

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13
Q

how do infants get immunity to n meningitdis

A

breat feeding passive immunity

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