Neisseria Flashcards
LOS
lipooligosaccharide has endotoxin activity
lipid A, core oligosaccharide
NO O-ANITGEN polysaccharide
LPS
lipopolysacchardie has O-antigen polysacchardide
virulence factor and function of Neisseria gonorrhoeae
- pilin- initial attachment to human cell
- pore protein- prevent phygolysosome in neutrophils
- opa protein - mediate film attachment to eukaryotic cell
- rmp protein- protects suface antigen from anitbodies
- Transferrin, Lactoferrin, hemoglobin binding protein- mediate iron to metabolism
- lipooligosacchardie- endotoxin activity
- IgA I protease- detroys immunoglobin A1
- B lactomase- hydolyses b lactamin ring
how is neisseria gonorrhea trasnmitted
sexual contact
gonorrhea infection in men
acute urethritis
purulent discharge
gonorrhea infection in women
endocervix
cervical disharge, abdominap pain
pelvic inflammatory disease- ectopic preg , sterile
gonorrhea oral infection
acquire during vaginal birth
resoior of gonorrhea
human
what increases the rsk of gonorrhea
multiple sex partners
what does neisseria meningitidis cause
meningitis
outer surface that N meningitidis have
- capsule
- pili
- lipooligosaccharide
n meningitidis resorvoi and how it spreada
humans, person to person, resp tract secretion
how do infants get immunity to n meningitdis
breat feeding passive immunity