Listeria

Question 1

Listeria is __ that can avoid antibody mediated clearance and able to survive to proteolytic enzymes, stomach acid and bile

Answer 1

facultative intracellular pathogen

Question 2

Virulence factors of Listeria

Answer 2

1. Internalin - surface protein (uptke into cells)
2. Act A - surface proteins that rearranges actin and listeria into adjacent cells
3. Listeriolysin O - hemolysin, lyses endosome
4. Phospholipase C - involved in escape from endosome

Question 3

__ is not effective against Listeria monocytogenes because__

Answer 3

1. humoral immunity

2. antibodies are not effective

Question 4

How can you get Listeriosis?

Answer 4

consuming undercooked processed meat
contaminated milk
unwashed veggies (cabbage)

Question 5

symptomps of Listeriosis?

Answer 5

most common is meningitis
mild flu like
infection occur in 3rd tri preggers when immunity is impaired

Question 6

Nomal flora for Listeria and how are humans infected?

Answer 6

soil, water, vegetation from animals and humans (gastrointestinal carriage)
humans are infected through food contaminatin, processed meat, raw veg

Question 7

what infectio occurs when Listeria dessiminates

Answer 7

meningitis