Staphylcocal Aureus

Question 1

Intoxication referes to what?

Answer 1

ingestion of toxin and not organism

Question 2

What is a clonal complex?

Answer 2

5-7 of shared housekeeping genes, alletic profile based , multi locust sequence type

Question 3

Staph toxin?

Answer 3

Heat stable, once its there it there
Prevent growth of Staph
Optimal growth is at 37-40C (no fever, dia, pain, nausea

Question 4

How do you prevent growth of Staph?

Answer 4

Wash hands, wear gloves
adequate refridgeration and heating
Dont’ wait too long in between
Preservatives

Question 5

Where do you find Sa?

Answer 5

We have Sa on skin, interior of nose, direct contact, skin fragments, respiratory, acne
Invade cells and live intracellularly- can survive extreme environments
Also found in bovines

Question 6

What are the disease characteristics of Sa?

Answer 6

Quick onset (30mins), self limiting 24-48 hours
Vomiting, nausea, diarrhea, abdominal pain

Question 7

Can Sa be used as bioterrrorism?

Answer 7

Yes, purified toxin can be used as bioterrorism

Question 8

What is the mechanism of of action for Sa toxin?

Answer 8

Toxin stimulates vagus nerve in the stomach that causes vomiting

Question 9

What are methods of foo preparation that might lead to more cases of Sa?

Answer 9

Food preparation→ improper refrigeration

Prevent with hand washing, refrigeration, preservatives

Question 10

What is MRSA?

Answer 10

Methicillin Resistant Sa ( MRSA)

Carry MecA gene→ necrotixing fascitis