Stains Flashcards
CK+/Vimentin+
RCC, clear cell type Endometrium Mesothelioma Salivary gland Thyroid Sweat gland Spindle cell carcinoma of any site
CK+/Vim-
RCC, chromophobe type Endocervix (adenocarcinoma) Lung carcinoma Breast Ovary Prostate Colorectum HCC
CK +/ EMA-
HCC (Cam5.2+, AE1/AE3–, CK903–) Adrenocortical neoplasms (frequently negative for all CKs) Most neuroendocrine neoplasms Embryonal carcinoma, yolk sac tumor Thyroid
CK-/EMA+
Meningioma Perineurioma Plasma cell neoplasms Anaplastic large cell lymphoma Popcorn or lymphocyte predominant (LP) cells [formerly L&H cells] in Hodgkin lymphoma RCC (sometimes)
CK+ non-epithelial tumours
Epithelioid sarcoma Synovial sarcoma Desmoplastic small round cell tumour