STAGES OF RBC DEVELOPMENT Flashcards
14 – 20
Proerythroblast / Rubriblast
12 – 17
Basophilic Normoblast/ Prorubricyte
10 – 15
Polychromatophilic Normoblast or Rubricyte
7 – 12
Orthochromic Normoblast/ Metarubricyte
7 – 10
Reticulocyte/ Polychromatophilic Erythrocyte/ Diffusely Basophilic Erythrocyte
deeply basophilic cytoplasm
Non-granular
Proerythroblast / Rubriblast
intensely basophilic cytoplasm
Basophilic Normoblast/ Prorubricyte
Blue-grey to pink-grey cytoplasm
Polychromatophilic Normoblast or Rubricyte
Last stage to undergo mitosis
Polychromatophilic Normoblast or Rubricyte
Start of Hb development
Polychromatophilic Normoblast or Rubricyte
Ciesla (dawn of hemoglobinization) – take up of iron
Polychromatophilic Normoblast or Rubricyte
Pink cytoplasm
Orthochromic Normoblast/ Metarubricyte
Mitotically inactive
Reticulocyte/ Polychromatophilic Erythrocyte/ Diffusely Basophilic Erythrocyte
Non-nucleated
Reticulocyte/ Polychromatophilic Erythrocyte/ Diffusely Basophilic Erythrocyte
Mature erythrocyte
Normal life span in the circulation: 120 days
Mature erythrocyte