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Hematology 1 Discussion > STAGES OF GRANULOCYTE DEVELOPMENT > Flashcards

STAGES OF GRANULOCYTE DEVELOPMENT Flashcards

1
Q

15-20

A

Myeloblast

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2
Q

15-21

A

Promyelocyte

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3
Q

12-18

A

Myelocyte

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4
Q

10-15

A

Metamyelocyte

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5
Q

9-15

A

Band (Stab or Staff Cell)
Segmented Neutrophils
Eosinophil

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6
Q

10-16

A

Basophil

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7
Q

Basophilic & scanty non-granular

A

Myeloblast

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8
Q

Basophilic & abundant

A

Promyelocyte

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9
Q

Primary granules start to appear

A

Promyelocyte

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10
Q

moderate amount w/ few specific granules

A

Myelocyte

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11
Q

Secondary granules start to appear

A

Myelocyte

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12
Q

Moderate to abundant w/ Specific granules (N, E, B) - insignificant cytoplasm

A

Metamyelocyte

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13
Q

Specific granules

A

Band

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14
Q

grainy cytoplasm (pink/rose-pink violet granules)

A

Segmented Neutrophils

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15
Q

red-orange refractile granules

A

Eosinophil

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16
Q

Sp. Granules contain histaminase (anti-parasitic), peroxidase (cyanide resistant), B-glucuronidase, arysulfatase, acid phosphatase (ACP), phospholipase, ribonuclease & cathepsin

A

Eosinophil

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17
Q

with few, large, densely-stained, dark purple to blue-black granules

A

Basophil

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18
Q

Granules contain heparin, Serotonin, peroxidase, histamine

A

Basophil

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19
Q

NUCLEOLI: 2-5

A

Myeloblast

20
Q

NUCLEOLI: 2-3

A

Promyelocyte

21
Q

NUCLEOLI: 3-4

A

Segmented Neutrophils

22
Q

(+) Non-Sp. Esterase, Peroxidase, & Sudan B

A

Myeloblast

23
Q

Counted w/ CBC

24
Q

Counter part: Retics

25
Q

Thick w/o filament formation

26
Q

Larger than RBC

A

Segmented Neutrophils

27
Q

Similar to band

A

Eosinophil

28
Q

Romanowsky Stain - stains early myelocytes to determine early maturation)

A

Eosinophil

29
Q
  • primarily in allergic rx
30
Q

Round or slightly oval Fine chromatin

A

Myeloblast

31
Q

Oval to round Slightly coarser chromatin pattern

A

Promyelocyte

32
Q

Oval to round Coarse chromatin

33
Q

Indented/kidney-bean shaped

A

Metamyelocyte

34
Q

Coarse & clumped chromatin

A

Metamyelocyte
Band
Segmented Neutrophils
Eosinophil

35
Q

Elongated or band-shaped

36
Q

Usually band or bilobed

A

Eosinophil

37
Q

round, indented, band or bilobed w/ smudged chromatin pattern

38
Q

hypersensitivity - excessive release of granules causing VASOCONSTRICTION

39
Q

stimulates chemotaxis

A

chemotactic factor a

40
Q

CFU-baso

41
Q

Basophil Life span: [?] (bone marrow); [?] (circulation); [?] (tissue)

A

7 days, 16 hrs, 9-18 months

42
Q

Similar to macrophage

43
Q

Basophil:

[?] (principal growth factor for baso dev’t)
[?]
[?] (stimulates baso dev’t)

A

IL-3
IL-5
CSF-GM

44
Q

Primarily in allergic rx

45
Q

Water-soluble

Hematology 1 Discussion (11 decks)

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