SSRIs Flashcards
Name the 8 SSRIs
Citalopram
Escitalopram
Fluoxetine
Fluvoxamine
Paroxetine
Sertraline
Vortioxetine
Vilazodone
Brand name of citalopram
Celexa
Brand name of Escitalopram
Lexapro
Brand name of fluoxetine
prozac
brand name of fluvoxamine
luvox
brand name of paroxetine
paxil
brand name of sertraline
zoloft
brand name of vortioxetine
trintellix
which 3 SSRIs cause increased sweating
citalopram
paroxetine
sertraline
what can increased doses of citalopram treat
binge eating
dosage range for citalopram
20-40mg in am with food
main off label use for citalopram
binge eating
what is the maximum dose of citalopram for patients over 60 and why
20mg daily due to QT prolongation
What baseline test should you get on patients starting citalopram who are over 40
ECG d/t prolongation risk
what is the max dose of citalopram in hepatic impairment
20mg qd
citalopram pregnancy risk
Low
what medications cannot be taken with citalopram d/t increased risk of QT prolongation
hydroxyzine
TCAs
Mellaril
Geodon
when is citalopram contraindicated
mania or seizures
what increases concentration of citalopram
prilosec
dosage range for escitalopram
10-20mg qd
what is the max dose of escitalopram for the elderly
10mg qd
pregnancy risk of escitalopram
low
which 2 SSRIs increase bleeding risk when taken with NSAIDs, ASA, or anticoagulants
escitalopram
sertraline
dosage range for fluoxetine
20-80 qam
dosage adjustments to fluoxetine for the elderly
start with 10mg
max dose 60mg
which SSRIs require ECG if QT prolongation risk
citalopram
escitalopram
fluoxetine
contraindications for fluoxetine
MAOIs
seizures
which SSRIs decrease the effectiveness of narcotic analgesics
fluoxetine
paroxetine
which SSRIs increase the concentration of THC
fluoxetine
fluvoxamine
starting dose for IR fluvoxamine
50mg
starting dose for ER fluvoxamine
100mg
dosage range for fluvoxamine
50-300mg qd
2 FDA approved uses of fluvoxamine
OCD
social anxiety
geriatric considerations for fluvoxamine
titrate slowly
pregnancy risk with fluvoxamine
low
which 3 SSRIs have to be tapered to dc
fluvoxamine
paroxetine
sertraline
fluvoxamine greatly increases the concentration of which meds
duloxetine
caffeine
dosage range for paroxetine
20-60mg at night with food
max dose of paroxetine for the elderly
40mg
Labs to monitor for paroxetine
creatinine and LDL
pregnancy risk for paroxetine
teratogenic
which antidepressant has the highest anticholinergic and sexual side effects
paroxetine
dosage range for sertraline
50-200mg qd with food
labs to monitor with sertraline
cholesterol
pregnancy risk for sertraline
low
sertraline effects on drug tests
can cause false positive for benzodiazepines
dosage range for vortioxetine
5-20mg daily
which SSRI is especially effective in the elderly
vortioxetine
pregnancy risk of vortioxetine
low
which SSRI is great for severe GAD
vorioxetine
which SSRI has the least sexual dysfunction side effects
vortioxetine
which SSRI has the potential for more drug interactions and why
fluoxetine as it has a marked effect on many CYP enzymes
which 2 SSRIs interfere w/ efficacy of opioids
fluoxetine and paroxetine
which SSRIs are the most selective inhibitors
citalopram
escitalopram
which 2 meds when administered together increases brain concentrations of norepinephrine
fluoxetine/olanzapine combo
which SSRI is not approved as an antidepressant and what is it approved for
fluvoxamine treats OCD
when is the period pf maximum risk and and why should you monitor closely
first few days-weeks after starting antidepressant and risk is higher for paradoxical suicide
congenital risks of SSRIs
none significant except with paroxetine
which SSRI can cause discontinuation syndrome in an infant
paroxetine
why are SSRIs good for elderly and chronically ill patients
little to no cardiotoxic, anticholinergic, antihistaminergic, or a-adrenergic adverse effects
Which SSRI has anticholinergic effects
paroxetine
which class of meds is particularly effective for post CVA depression
SSRIs
which SSRI is consistently effective in youths
fluoxetine
which 4 SSRIs are approved for OCD in patients 18+
fluvoxamine, paroxetine, sertraline, and fluoxetine
which 3 SSRIs are approved for OCD in youths
fluvoxamine, fluoxetine, and sertraline