Dementia meds and TD management

Question 1

brand name of donepezil

Answer 1

Aricept

Question 2

brand name of memantine

Answer 2

namenda

Question 3

dosage of aricept

Answer 3

initial 5mg qd
increase to 10mg after 4-6 weeks
max 23mg qd

Question 4

approved uses of aricept

Answer 4

mild, moderate, and severe dementia

Question 5

how long does it take to see improvement with donepezil

Answer 5

can take up to 6 weeks

Question 6

labs to monitor with donepezil

Answer 6

possible EKG for QT prolongation

Question 7

dosage of memantine

Answer 7

5-20mg QAM

Question 8

labs to monitor with memantine

Answer 8

CMP

Question 9

side effects of memantine

Answer 9

hallucinations
confusion
aggression

Question 10

which meds can be used to manage TD

Answer 10

benztropine
ingrezza
austedo

Question 11

brand name for benztropine

Answer 11

cogentin

Question 12

dosage of benztropine for EPS

Answer 12

2-8mg qd
start with 1-4mg BID or once

Question 13

dosage of benztropine for parkinsonism

Answer 13

0.5-6mg qd
start w/ 0.5mg
increase by 0.5mg q 5-6 days

Question 14

pregnancy risk with benztropine

Answer 14

avoid
stop at least 5 days prior to lactation

Question 15

contraindications for benztropine

Answer 15

angle closure glaucoma
pyloric or duodenal obstruction
stenosing peptic ulcer
prostate hypertrophy
bladder neck obstruction
megacolon

Question 16

which medication works best for rigidity and dystonia

Answer 16

benztropine

Question 17

Name the cholinesterase inhibitors

Answer 17

Donepezil
Galantamine
Rivastigmine

Question 18

dosing of galantamine

Answer 18

4mg q12h x 4 weeks
8mg q12h x4 weeks
12mg q12h

Question 19

what dosages are available for galantamine ER (daily)

Answer 19

8mg, 12mg, 24mg

Question 20

taper up of rivastigmine

Answer 20

1.5mg BID x4 weeks
3mg BID x4 weeks
4.5mg BID x4 weeks
6mg BID

Question 21

what dosages are available for the exelon patch

Answer 21

4.6mg and 9.5mg

Question 22

common side effects of cholinesterase inhibitors

Answer 22

N/V
diarrhea
anorexia
bradycardia

Question 23

namenda (memantine) taper to start

Answer 23

5mg q12h x7 days
5mg qam and 10mg qpm x7 days
10mg q12h

Question 24

mechanism of action for memantine

Answer 24

NMDA glutamate receptor antagonist

Question 25

upwards taper of donepezil

Answer 25

5mg qd x4 weeks then increase to 10mg
there is also a 23mg formulation

Question 26

brand name for donepezil

Answer 26

Aricept

Question 27

brand name for galantamine

Answer 27

razadyne

Question 28

brand name for rivastigmine

Answer 28

exelon

Question 29

brand name for memantine

Answer 29

namenda