Dementia meds and TD management Flashcards

1
Q

brand name of donepezil

A

Aricept

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2
Q

brand name of memantine

A

namenda

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3
Q

dosage of aricept

A

initial 5mg qd
increase to 10mg after 4-6 weeks
max 23mg qd

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4
Q

approved uses of aricept

A

mild, moderate, and severe dementia

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5
Q

how long does it take to see improvement with donepezil

A

can take up to 6 weeks

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6
Q

labs to monitor with donepezil

A

possible EKG for QT prolongation

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7
Q

dosage of memantine

A

5-20mg QAM

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8
Q

labs to monitor with memantine

A

CMP

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9
Q

side effects of memantine

A

hallucinations
confusion
aggression

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10
Q

which meds can be used to manage TD

A

benztropine
ingrezza
austedo

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11
Q

brand name for benztropine

A

cogentin

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12
Q

dosage of benztropine for EPS

A

2-8mg qd
start with 1-4mg BID or once

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13
Q

dosage of benztropine for parkinsonism

A

0.5-6mg qd
start w/ 0.5mg
increase by 0.5mg q 5-6 days

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14
Q

pregnancy risk with benztropine

A

avoid
stop at least 5 days prior to lactation

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15
Q

contraindications for benztropine

A

angle closure glaucoma
pyloric or duodenal obstruction
stenosing peptic ulcer
prostate hypertrophy
bladder neck obstruction
megacolon

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16
Q

which medication works best for rigidity and dystonia

A

benztropine

17
Q

Name the cholinesterase inhibitors

A

Donepezil
Galantamine
Rivastigmine

18
Q

dosing of galantamine

A

4mg q12h x 4 weeks
8mg q12h x4 weeks
12mg q12h

19
Q

what dosages are available for galantamine ER (daily)

A

8mg, 12mg, 24mg

20
Q

taper up of rivastigmine

A

1.5mg BID x4 weeks
3mg BID x4 weeks
4.5mg BID x4 weeks
6mg BID

21
Q

what dosages are available for the exelon patch

A

4.6mg and 9.5mg

22
Q

common side effects of cholinesterase inhibitors

A

N/V
diarrhea
anorexia
bradycardia

23
Q

namenda (memantine) taper to start

A

5mg q12h x7 days
5mg qam and 10mg qpm x7 days
10mg q12h

24
Q

mechanism of action for memantine

A

NMDA glutamate receptor antagonist

25
Q

upwards taper of donepezil

A

5mg qd x4 weeks then increase to 10mg
there is also a 23mg formulation

26
Q

brand name for donepezil

27
Q

brand name for galantamine

28
Q

brand name for rivastigmine

29
Q

brand name for memantine