Dementia meds and TD management Flashcards
brand name of donepezil
Aricept
brand name of memantine
namenda
dosage of aricept
initial 5mg qd
increase to 10mg after 4-6 weeks
max 23mg qd
approved uses of aricept
mild, moderate, and severe dementia
how long does it take to see improvement with donepezil
can take up to 6 weeks
labs to monitor with donepezil
possible EKG for QT prolongation
dosage of memantine
5-20mg QAM
labs to monitor with memantine
CMP
side effects of memantine
hallucinations
confusion
aggression
which meds can be used to manage TD
benztropine
ingrezza
austedo
brand name for benztropine
cogentin
dosage of benztropine for EPS
2-8mg qd
start with 1-4mg BID or once
dosage of benztropine for parkinsonism
0.5-6mg qd
start w/ 0.5mg
increase by 0.5mg q 5-6 days
pregnancy risk with benztropine
avoid
stop at least 5 days prior to lactation
contraindications for benztropine
angle closure glaucoma
pyloric or duodenal obstruction
stenosing peptic ulcer
prostate hypertrophy
bladder neck obstruction
megacolon
which medication works best for rigidity and dystonia
benztropine
Name the cholinesterase inhibitors
Donepezil
Galantamine
Rivastigmine
dosing of galantamine
4mg q12h x 4 weeks
8mg q12h x4 weeks
12mg q12h
what dosages are available for galantamine ER (daily)
8mg, 12mg, 24mg
taper up of rivastigmine
1.5mg BID x4 weeks
3mg BID x4 weeks
4.5mg BID x4 weeks
6mg BID
what dosages are available for the exelon patch
4.6mg and 9.5mg
common side effects of cholinesterase inhibitors
N/V
diarrhea
anorexia
bradycardia
namenda (memantine) taper to start
5mg q12h x7 days
5mg qam and 10mg qpm x7 days
10mg q12h
mechanism of action for memantine
NMDA glutamate receptor antagonist
upwards taper of donepezil
5mg qd x4 weeks then increase to 10mg
there is also a 23mg formulation
brand name for donepezil
Aricept
brand name for galantamine
razadyne
brand name for rivastigmine
exelon
brand name for memantine
namenda