SSI & Wound Healing

Question 1

Chronic Wounds andtheHealing Processes The first step after initial wounding initiates

Answer 1

coagulation to form a blood clot in the wound bed (also known as hemostasis).

Question 2

After hemostasis The subsequent wound healing process can be divided into three overlapping phases:

Answer 2

inflammation, proliferation, and maturation .

Question 3

What happen During the inflammation phase in wound healing

Answer 3

blood vessels dilate to allow the entry of a variety of cells into the wound area. These include important cells of the immune system, including white blood cells such as macrophages and neutrophils, which produce a variety of enzymes, cytokines, and growth factors that are essential for the wound healing process. At this stage, the first clinical signs of healing become visible such as heat, erythema, edema, and pain.

Question 4

What happened During the proliferation phase in wound healing?

Answer 4

the wound is rebuilt with the formation of new granulation tissue, the extracellular matrix reforms with collagen secreted by fibroblasts, and new blood vessels emerge (angiogenesis). Subsequently, reepithelialization occurs through the migration of keratinocytes at the surface of the wound to complete this phase.

Question 5

After complete wound closure, what happen durong the final maturation phase?

Answer 5

remodels collagen and decreases blood vessels inside the scar tissue

Question 6

Secondary intention — Indications for secondary closure (ie, by granulation) include:

Answer 6

Deep stab or puncture wounds that cannot be adequately irrigated
●Contaminated wounds
●Abscess cavities
●Presentation after a significant delay (eg, >24 hours) (see ‘Wound age’ above)
●Noncosmetic animal bites