Sporozoans Flashcards
Oval in shape (25-35 um), cell wall has 2 layers
Young oocyst will develop 2 sporoblasts -> matured oocyst will contain 2 sporocyst. Each sporocyst will contain 4 sausage shape sporozoites
Isospora belli
Isospora belli
Oocyst:
Transparent and oval
MOT: Ingestion of ripe oocyst from contaminate water and food
Isospora belli
Disease associated in Isospora belli
Human coccidiodes
Habitat: Intestine Diarrhea/asymptomatic
Isospora belli
Sarcocystis (lindemanni)
Oocyst:
Sausage shape sporocyst
Ovoidal in shape mature oocyst has 4 sporozoites
Sarcocystis (lindemanni)
MOT: Ingestion of Bradyzoites from the infected muscle
Sarcocystis (lindemanni)
Disease associated in Sarcocystis (lindemanni)
Sarcocystosis or sarcosporidiosis
Habitat: Can be found on uncooked pork or cattle, striated muscle
Sarcocystis (lindemanni)
Manifestation: Fever, diarrhea, abdominal pain
Sarcocystis (lindemanni)
Roundish (4-6 um in size), small number/usually none sporocyst, 4 sporozoite, dark granules in the middle
Cryptosporidium parvum
Oocyst: Thick cell wall 1-6 dark granules
Cryptosporidium parvum
Cryptosporidium parvum
Infective stage:
Oocyst
MOT: Ingestion of oocyst from fecally contaminated water and food
Cryptosporidium parvum
Disease associated in Cryptosporidium parvum
Cryptosporidiosis
Found in immunocompromised individual (full blown AIDS) along with Cryptosporidium spp.
Blastocystis hominis
Centrally located large vacuole 2-4 nuclei at the
periphery
Blastocystis hominis
MOT: Ingestion of contaminated food and water
Blastocystis hominis
Microsporidia’s Spore
Polar filaments “Extruding”
Initiate infection by injecting sporoplasm (infectious material) on the host
Microsporidia
May be found on the feces and patient with full blown AIDS
Microsporidia
Microsporidia
Manifestation:
Enteritis, Keratoconjunctivitis
Tachyzoite (crescent shape) and Bradyzoite (enclose to for cyst)
Toxoplasma gondii
Seen on cats, intracellular (can infect RBC including macrophage)
Toxoplasma gondii
MOT: ingestion oocyst, transplacental transmission
Toxoplasma gondii
Toxoplasma gondii
Disease:
Toxoplasmosis
Toxoplasma gondii
Manifestation:
fatigue, fever, myalgia
Found in the alveolar spaces of the lung tissue, spleen, lymph nodes in bone marrow
Pneumocystis jirovecii
Can infect children, patient with full blown AIDS, immunocompromised individuals
Pneumocystis jirovecii
Trophozoite 4-8 unorganized nuclei in rosette
Pneumocystis jirovecii
Circular in shape
The same with E. histolytica
Pneumocystis jirovecii
MOT: Unknown (could be transmitted person to person)
Pneumocystis jirovecii
Direct fecal smear/Concentration techniques
intestinal sporozoans
Kinyoun’s Acid Fast
P. jirovecii
Serological test
PCR-test, ELISA, IFAT, IHA
Muscle biopsy
toxoplasma