Spleen and Thymus I

Question 1

accessory spleen

Answer 1

common finding

embryologic, acquired, rupture

Question 2

splenectomy look for

Answer 2

accessory spleen

if have one - splenectomy will not work

Question 3

most common liver disease

Answer 3

cirrhosis from alcohol

HTN arterioles - portal HTN back P to venous system

congested splenomegaly

Question 4

function of spleen

Answer 4

filter blood

-site of immune responses to blood borne antigens

Question 5

open circulation spleen

Answer 5

slow flow
-red pulp

cell removal

Question 6

cords of billroth

Answer 6

removal of RBCs in splenic cords

Question 7

splenic follicles

Answer 7

sites of B cell maturation

but major site - lymph noes

Question 8

mononuclear phagocyte system

Answer 8

spleen

liver, spleen, BM, lymphatics

Question 9

closed circulation spleen

Answer 9

majority of bloodflow

-fast

Question 10

spleen immune function

Answer 10

dendritic present to T cells

-T and B cells interact edges of white pulp follicles - get Ab secreting plasma cells

Question 11

splenomegaly

Answer 11

up to 80-90% of platelet mass may be sequestered in red pulp

lead to thrombocytopenia

Question 12

hypersplenism

Answer 12

large spleen leads to cytopenia

Question 13

splenic macros

Answer 13

pitting of RBCs

-remove heinz bodies and howell jolly bodies

Question 14

splenectomy risk

Answer 14

infection from encapsulated bacteria

• pneumococci
• meningococci
• haem influenza

give pneumovax

Question 15

EMH

Answer 15

can be in spleen

Question 16

run long distance with LUQ pain

Answer 16

blood sequestered to spleen

Question 17

dragging sensation in LUQ and discomfort after eating

Answer 17

splenomegaly

Question 18

anemia, leukopenia, thrombocytopenia

Answer 18

seen in hypersplenism

Question 19

salmonella

Answer 19

typhoid

Question 20

colon carcinoma

Answer 20

liver mets
-spleen spared**

spleen is rarely site of metastatic foci

Question 21

shaggy exudates

Answer 21

nonspecific splenitis of various blood borne infecdtions

Question 22

EBV

Answer 22

mononucleosis

Question 23

amyloidosis

Answer 23

primary inflammatory disease

-can lead to splenomeglay

Question 24

splenic rupture

Answer 24

more common with mono, malaria, typhoid, lymph neoplasms

less common with chronic conditions

Question 25

most common cause of death splenomegaly

Answer 25

mono-rupture spleen

-health care provider manipulation

Question 26

non-specific acute splenitis

Answer 26

reaction to blood-borne infection

mild splenomeglay
soft and fluctuant
acute congestion of red pulp
neutro, plasma, eosino infiltrates

Question 27

mild splenomegaly, soft and fluctuant, acute congestion of red pulp, neutros, plasmas, and eosinos

Answer 27

non-specific acute splenitis

Question 28

schistosomiasis

Answer 28

parasitic infection

pipe stem hepatic fibrosis

severe congestive splenomegaly

Question 29

congestive splenomegaly

Answer 29

with cardiac decompensation - right side failure

cirrhosis of liver - alcoholic

obstruction of extrahepatic portal or splenic vein - spontaneous vein thrombosis or compression by tumor

Question 30

left HF

Answer 30

more common

Question 31

pyelophlebitis

Answer 31

portal vein inflammation

may lead to congestive splenomegaly

Question 32

moderate enlargement of spleen

Answer 32

vascular congestion

or obstruction of extrahepatic portal or splenic vein

Question 33

massive splenic enlargement

Answer 33

with liver cirrhosis

Question 34

start on

Answer 34

slide 11 of thymus and spleen slides