Spironolactone Flashcards

1
Q

Class of spironolactone

A

Aldosterone-dependent potassium sparing diuretic

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2
Q

Spironolactone is a competitive inhibitor of … which prevents … exchange at the … & …

A
  • aldosterone-MR
  • Na/K exchange
  • DTs
  • CDs
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3
Q

Indications of spironolactone (4)

A
  • oedema
  • ascites
  • 1ry hyperaldosteronism
  • nephrotic syndrome
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4
Q

Contraindications of spironolactone (3)

A
  • hyperK
  • hypoNa
  • Addison’s
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5
Q

Spironolactone should not be given to the elderly if they have

A

Renal impairment

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6
Q

Side effects of spironolactone (4)

A
  • hyperK
  • hypogonadism
  • impotence
  • menstrual irregularities
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