Amiodarone Flashcards
1
Q
Class of amiodarone
A
Class III antiarrythmic
2
Q
Mechanism of amiodarone
A
Non-selective inhibitor of Na, Ca & a-adrenoreceptor channels —> prolongs AP
3
Q
Effect of amiodarone on ECG
A
+ QT
4
Q
Indications of amiodarone (4)
A
- rhythm control AF
- atrial flutter
- v tachycardia
- tachyarrythmias (associated w/ WPW syndrome)
5
Q
Contraindications of amiodarone (3)
A
- sinus bradycardia
- atrial heart block
- thyroid dysfunction/iodine sensitivity
6
Q
IV amiodarone not suitable for (2)
A
- resp & cardiac failure
- severe arterial hypotension
7
Q
Side effects of amiodarone
A
- thyroid issues
- pulm fibrosis
- peripheral neuropathy
- phototoxicity
- optic neuritis
- hepatotoxicity
- skin discolouration
8
Q
Important drug interaction with amiodarone
A
Warfarin —> + anticoagulation
9
Q
Excretion of amiodarone
A
Faeces
10
Q
When to discontinue amiodarone
A
Neuritis/neuropathy
