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Clinical Bacteriology Lec > Spirochetes > Flashcards

Spirochetes Flashcards

1
Q

“Spiro” means ____ and “chaete” means
____

A

“Spiro” means “coiled” and “chaete” means
“hair”

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2
Q

Slender, spiral-shaped bacteria containing one or more complete rotations that forms a helix

A

SPIROCHETES

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3
Q

-permit a corkscrew like motility on spirochetes

A

Periplasmic fibrils or axial filaments

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4
Q

Most spirochetes species stain poorly with __ staining or ___ methods

A

Gram staining or Giemsa methods

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5
Q

spirochetes spp are best observed with the use of

A

dark field or phase-contrast microscopy.

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6
Q

spirochetes 3 genus

A

treponema, borrelia, leptospira

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7
Q

treponema associated disease

A

syphilis, bejel, yaws, pinta

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8
Q

borrelia associated disease

A

Lyme disease (borreliosis)
epidemic relapsing fever
endemic relapsing fever

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9
Q

leptospira genus associated disease

A

leptospirosis (wells disease)

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10
Q

Most prevalent of the nonvenereal (non sexually transmitted] treponematoses)

A

yaws

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11
Q

Also called frambesia tropica, pian, parangi, paru, buba, or bouba

A

yaws

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12
Q

yaws is caused by what subsp

A

T.pallidum subsp.Pertenue

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13
Q

Contracted chiefly during childhood by direct contact, with breaks in the skin allowing entry pf treponemes

A

yaws

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14
Q

also called bejel

A

Endemic Syphilis

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15
Q

is a Nonvenereal chronic infection

A

Endemic Syphilis

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16
Q

Endemic Syphilis is caused by what subsp

A

T.palidum subsp.endemicum

17
Q

transmitted by direct contact with active lesions, contaminated fingers, and eating or drinking utensils

A

endemic syphilis

18
Q

also called Carate, mal de pinto, azul

A

pinta

19
Q

pinta is caused by what subsp

A

t. carateum

20
Q

Via nonvenereal skin or mucous membrane contact

A

pinta

21
Q

manifestations of pinta

A

hypopigmented skin lesions

22
Q

Transmission of this disease occurs by direct contact with active lesions (sexual contact)

A

Syphilis

23
Q

second most common mode of infection of syphilis
may result when a latently infected female becomes pregnant, or when a pregnant woman becomes infected

A

Vertical transmission across the placenta,

24
Q

other ways of syphilis transmission

A

blood transfusion, needle stick, improper handling in the lab

25
Q

The word syphilis comes from a poem written in 1530 that described a mythical shepherd named ____, who was offlicted with the disease as punishment for cursing the gods.

A

Syphilus

26
Q

Stages of Syphilis

A

primary, secondary, tertiary

27
Q

stage where chance is characteristically ulcerated with raised, firm edges and a smooth base and is notable for absences of an exudate or pain

A

primary

28
Q

Appearance of the rash on the palms and soles is characteristic

A

secondary

29
Q
  • tissue destruction
  • becomes evident decades after the primary infection
A

tertiary

30
Q

used for direct sampling of lesions for lab diagnosis of trepanematoses

A

darkfield microscopy

31
Q

Infections involved in tertiary spirochetes

A

Cardiovascular syphilis
Syphilitic gummas
Parenchymatous neurosyphilis

32
Q

Direct sampling of lesions

A

Darkfield Microscopy

33
Q

labeled antibodies specific for T.pallidum

A

Fluorescein isothiocyanate (FITC)

34
Q

Lab diagnosis for Tissue fluid that has been dried and fixed to the slide

A

Fluorescence Microscopy

35
Q

These tests have been used traditionally to screen
or disease and to monitor the course of the
disease after treatment.

A

Nontreponemal Serologic Tests

36
Q

Nontreponemal Serologic standard tests include the

A

• VDRL, rapid plasma reagin (RPR), unheated serum reagin (USR), toluidine red unheated serum (TRUST)
• Wassermann complement fixation test
• Kahn tube flocculation test

37
Q

Treponemal Serologic Tests

A

• Fluorescent treponemal antibody absorption
test (FTA-ABS)
• Microhemagglutination - T.pallidum test
(MHA-TP)

Clinical Bacteriology Lec (5 decks)

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