Spinal disorders Flashcards
What is myelopathy?
Damage to the spinal cord
What is myelitis?
Inflammation of the sPINAL CORD
What are the general signs that indicate spinal cord lesion?
Mixed UMN and LMN signs
Sensory signs
Sphincter involvement
Autonomic dysfunction
Bilateral, asymmetrical signs
What are the red flags for back pain?
Focal neurological deficit
History of trauma
Osteoporosis
Pain at night
Unexplained weight loss
History of malignancy
Fever
Thoracic pain
What are the signs of UMN lesion?
Weakness
Spastic paresis
Disuse atrophy
No fasciculations
Hyperreflexia
Hypertonia
Extensor plantar response (Babinski sign)
Upper limb: strong flexors, weak extensors
Lower limb: strong extensors, weak flexors
What are the signs of LMN lesion?
Weakness
Flaccid paresis
Wasting atrophy
Fasciculations
Hyporeflexia
Hypotonia
Flexor plantar response
What are the sensory signs of spinal cord pathology?
Ipsilateral: loss of touch, vibration and joint position sense
Contralateral: loss of pain and temperature sensation
What are some causes of myelopathy?
Tumour
Degenerative disease
Trauma
Vascular abnormalities
Demyelination
Autoimmune
Infection
B12 deficiency
Malignancy
Idiopathic
What is the presentation of B12 deficient myelopathy?
Hands and feet paraesthesia
Areflexia
First UMN signs- extensor plantars
Degeneration of:
- Corticospinal tracts → paraplegia
- Dorsal columns → sensory ataxia
Painless retention of urine
What is the classification of spinal disorders?
Congenital
Infection
Tumour
Emergency
Injury (trauma)
What are the types of spinal congenital anomalies?
Spina bifida
Tethered cord syndrome
What is spina bifida?
Birth defect in which there is incomplete closure of the spine
What is the clinical embryology of spina bifida?
Anterior neuropore failure to close at 24 days= anencephaly
Posterior neuropore failure to close at 26 days = spina bifida
What blood tests i done during pregnancy to identify open neural tube defects?
Alpha fetoprotein obtained from amniocentesis at 16 weeks of pregnancy
What are the risk factors for spina bifida?
- Low levels of folic acid during early pregnancy
- FH
- Diabetes
- Obesity
- Anti-seizure drugs
What is the classification of spina bifida?
Spina bifida occulta- closed
Spina bifida aperta- open
- Meningocele
- Myelomeningocele
What are the features of meningocele?
Lumbosacral
Sac covering is normal skin
Sac contains CSF
Translucent
No neurological deficit
Intact sphincters
Uncommon associated hydrocephalus
What are the features of myelomeningocele?
Lumbosacral
Sac covering is membranous
CSF and neural tissue
Transopaque
Neurological deficit
Double incontinence
Associated hydrocephalus
What is the clinical presentation of spina bifida?
Abnormal tuft of hair
Back swelling
Lower limb deficits- paraplegia
Sensory deficits- hypoesthesia
Sphincter distubrnace- incontinence
Back deformities- scloiosis
Lower limb deformities- clubbed feet