Spinal Cord Morphology Flashcards
Shallow longitudinal groove in which dorsal rootlets enter the spinal cord on its posterolateral surface
posterolateral sulcus
Ventral rootlets leave spinal cord from these structures
anterolateral sulcus
Contains the cell bodies of the primary sensory neurons of that particular spinal nerve
dorsal root ganglion
Join to form spinal nerves
Dorsal and ventral roots
Portion of the spinal cord that gives rise to a spinal nerve
segment
Breakdown of the 31 spinal segments of the spinal cord
8 - cervical 12 - thoracic 5 - lumbar 5 - sacral 1 - coccygeal
Cervical enlargement (spinal cord)
Supplies the upper extremities, extends from C5-T1
Lumbar enlargement (spinal cord)
Supplies the lower extremities, extends from L2-S3
What are funiculi generally in the spinal cord?
white matter columns in between the gray mater areas
You have the anterior, lateral, and posterior funiculi
Where do you have lateral gray horns in the spinal cord?
Levels of the 12 thoracic and upper 2 or3 segments of lumbar nerve roots
Structure through which the corticospinal tract descends
Lateral funiculus
Principle targets are neurons in the anterior gray horn concerned with activation of skeletal muscles
Structures through which the posterior column of medial lemniscus (PCML) ascend
Gracile and cuneate fasciculi
Composition of fasciculi
Composed of the central processes of peripheral sensory neurons supplying muscles, joints, and skin
Areas of the body from which processes enter the gracile fasciculus and cuneate fasciculus, respectively
Processes entering from the lower part of the body form the gracile fasciculus; those from the upper part form the cuneate fasciculus
Gray matter columns in the spinal cord
1) Posterior (Dorsal) Horn
2) Intermediate Gray / Intermediate Zone
3) Anterior Horn
Column/root containing alpha and gamma (lower) motor neurons
Ventral Gray Column / Ventral Horn
Spinal cord structures containing preganglionic cells for the autonomic nervous systems
Intermediolateral gray columns/horns
These segments give rise to sympathetic axons that leave the spinal cord within the ventral roots and then travel to the sympathetic ganglia via the white rami communicantes
T1-L2
From segments S2-4, these axons leave the spinal cord within the sacral ventral roots
Sacral parasympathetic neurons
Lissauer’s Tract
Compact bundle of small fibers which are part of the pain pathway in the dorsolateral fasciculus of the spinal cord
Where is the proportion of gray to white matter greatest in the spinal cord
lumbar and cervical enlargements
General trend with spinal lamina (what is where generally?)
Dorsal: sensory
Intermediate Areas: autonomics
Ventral: motor
Describe the medial stream of afferent fibers into lamina of rexed
- Comprised of medium/large fibers which divide within posterior funiculus into asc/desc branches
- Branches swing into the post. gray horn and synapse in Lamina II, III, IV
- Largest ascending fibers run all the way to the posterior column nuclei in the medulla oblongata
- Long fibers form bulk of gracile/cuneate fasciculi
Describe the lateral stream of afferent fibers into lamina of rexed
- Comprised of small (Aδ and C) fibers which divide into short ascending/descending branches with the posterolateral tract of Lissauer
- Synapse upon neurons in the Marginal Zone (Lamina I) and Substantia Gelatinosa (Lamine II)
- Some fibers synapse upon dendrites of Laminae III-V
Give rise to anterior and posterior spinal arteries (respectively, I think)
Vertebral and Radicular (esp Great Radicular Artery of Adamkiewicz) Arteries
Give rise to spinal arterial plexus
Anterior and Posterior Spinal Arteries
Knee-Jerk Reflex. ___ type fiber endings in quadriceps muscle spindles are exited and in turn excite quadriceps ____ motor neurons
Ia type fibers
alpha motor neurons
General principle of reciprocal inhibition in reflexes
Reflex activity in a given muscle produces similar activity in its ipsilateral synergists and the opposite activity in its ipsilateral antagonists.
Principal Cord Segment Tested: biceps reflex
C5
Principal Cord Segment Tested: brachioradialis reflex
C6
Principal Cord Segment Tested: triceps reflex
C7
Principal Cord Segment Tested: knee-jerk reflex (patellar)
L4
Principal Cord Segment Tested: ankle-jerk reflex (achilles)
S1
Autogenic inhibition
Alpha motor neurons that innervate the muscle connected to the relevant golgi tendon organ are inhibited via inhibitory interneuron between the afferent and efferent fibers.
Two ways which flexor reflex pathways spread over multiple spinal segments
1) Primary afferent fibers bifurcate on entering the spinal cord and their processes then extend one or more segments in both rostral and caudal directions
2) flexor pathway includes at least one interneuron, which itself may have processes extending over several segments
Crossed effects of a flexor reflex
Simultaneous and opposite pattern of activity in the contralateral limb; As the left left leg flexes and withdraws, the right leg extends and is thus better able to support the body