Spinal Cord and Periphery Flashcards
What are the 3 columns of white matter?
Posterior
Lateral
Anterior
What are ascending pathways?
Sensory
What are descending pathways?
Motor
What is the role of the corticospinal/pyramidal tract?
Carries motor impulses from motor cortex to skeletal muscles
What is the role of the posterior/dorsal column?
Carries touch, tactile localisation, vibration sense, proprioception
What is the role of the lateral spinothalamic tract?
Pain and temperature
Where does the pathway of the pyramidal tract start?
From motor cortex (area 4)
What happens to corticobulbar fibres?
Go to contralateral cranial nerve nucleii
Where do corticospinal fibres cross?
Decussation of pyramids
What is the site of lower motor neurons?
Ventral horn
What does the dorsal column carry?
Sensations of: Fine touch Tactile localisation Vibration sense Proprioception
How does the 1st order neuron end? (dorsal column)
Synapses with the cell body of the 2nd neuron
Where is the cell body of the 2nd neuron situated? (dorsal column)
Lower part of the medulla
Where does the 2nd order neuron cross over? (dorsal column)
Medulla
What is the tract known as after the 2nd order neuron decussates? (dorsal column)
Medial lemniscus
What does the medial lemniscus pass through?
Medulla, pons, midbrain to reach the thalamus
Where does the 3rd order neuron start? (dorsal column)
Thalamus
Where do axons of the 3rd order neuron pass? (dorsal column)
Axons pass through the internal capsule and radiate to the post-central gyrus (Area 2, 1, 3)
Where does the first order neuron enter and end? (lateral spinothalamic tract)
Enters into the grey matter and ends at the same level
Where does the 2nd order neuron end? (lateral spinothalamic tract)
Thalamus
Where does the 3rd order neuron pass through? (lateral spinothalamic tract?
Internal capsule
Radiation to reach post-central gyrus
Where does decussation occur in the lateral spinothalamic tract?
At the level of entry
What is a reflex?
Involuntary pattern of response in result of a sensory stimulus
Where are reflexes mediated?
At the level of spinal cord
What happens in the stretch reflex?
- tendon stretched
- intrafusal muscle fibres stimulated
- sensory neuron activated
- monosynaptic reflex arc
- polysynaptic reflex arc to inhibitory interneuron - muscle contraction
- reciprocal innervation
Why is the stretch reflex important?
Important in control of muscle tone and posture
What happens in the flexor reflex?
- pain stimulus
- sensory neuron activated
- polysynaptic reflex arc
- flexion and withdrawal from noxious stimulus
- crossed extensor response to contralateral limb (only in weight bearing limbs)
What mediates reflexes?
Lower motor neurons
What happens to reflexes when there is an UMN lesion with LMN unaffected?
Reflexes are exaggerated
How does UMN lesion and LMN lesions affect muscle tone?
UMN lesion = increased tone (spasticity)
LMN lesion = decreased tone (flaccidity)
Where is a lesion located the signs and symptoms are contralateral?
Above the level of decussation
What happens if a lesion is below the level of decussation?
Signs and symptoms are ipsilateral
What are the signs of a left UMN lesion at the internal capsule?
Right sided paralysis
Hyper-reflexia
Increased tone
What are the signs of a left UMN lesion at the upper cervical spinal cord?
Left sided paralysis
Hyper-reflexia
Increased tone
What are the signs of a left LMN lesion?
Left sided paralysis
Absent reflexes
Flaccid
Is motor neuron disease an UMN or LMN?
LMN
What is MND?
A group of diseases affecting the LMN in the ventral horn of the spinal cord
Neuron dies = muscle atrophy
What would happen if there was a lesion in the left internal capsule affecting the dorsal column?
Right sided sensory loss
What would happen if there was a lesion at left cervical spinal cord affecting the dorsal column?
Left sided sensory loss
What would happen with a lesion in the left internal capsule affecting the lateral spinothalamic tract?
Right sided pain and temperature loss
What would happen with a lesion in the left cervical spinal cord affecting the lateral spinothalamic tract?
Left sided pain and temperature loss