spiegel 3 Flashcards
most common primary brain tumor > 60
glioblastoma multiforme
OCD abnormal brain regions
caudate
thalamus
orbitofrontal cortex
Anton’s syndrome
“I’m not blind”
stroke: occipital lobes
Riluzole
med for ALS, targets glutamate
most common CNS cancer with AIDS
lymphoma
Most frequent CNS opportunistic infection in AIDS
toxoplasmosi
most common spinal cord pathology in AIDS
vacuolar myelopathy
demyelinating in AIDS
PML
Devics
form of MS
ipsilateral horners, contralateral hemiparesis, headache
carotid occlusion
compare 2 groups to see if chance or not
analysis of variance
bells palsy frequent cause
herpes simplex
bipolar and gender
equal rates
tourettes med
pimozide, D antagonist
Kohut
Parents mirror child as a form of empathy
Depression with increased appetite, weight gain, increased sleep
atypical, use MAOI
BPRS
brief psychiatric rating scale
for schizo and psychosis
Donepezil MOA
AchE inhibitor
aggression neurotransmitters
decreased serotonin, increased dompamine
Klein Levin
sleepy, fat, irritable
pure motor hemiparesis stroke location
contralateral internal capsule
Auscultate head bruit
AVM
arterio venous malformation
Hallervarn Spatz
iron in the basal ganglia. Dementia, parkinsons
Alcohol blackout memory issues
anterograde amnesia
neurotransmitter that localizes to basal forebrain and responsible for memory, attention, executive function
acetylcholine
mirtazapine MOA
alpha 2 blockade
anti-nausea via 5 HT3 antagonism
GABA A receptor is what ion channel
chloride
Botulinum poisoning
dysphagia, dysarthria, ptosis, diplopia, urinary retention
cocaine and seizures
decreases threshold in intoxication
what dx most likely to complete suicide
MDD
Meige’s syndrome
blephorospasm and oromandibular dystonia
Scanning speech
cerebellar issue
of the somatoform disorders what is the best prognosis
conversion disorder
least anticholinergic TCA
desipramine
Vagal nerve stimulator FDA approved for
epilepsy, MDD
Balint syndrome
Optic ataxia. Oculomotor apraxia. Simultagnosia.
what spot needs minimal damage to cause loss of consciousness
reticular activating system
low B12 causes
damage to spinal cord and peripheral nerve pathology
men: cause of increased risk of cardiovascular disease
hostility
TMS approved after
failed one antidepressant
why atypicals less EPS- hypothesis
fast off
conversion disorder risk factors
rural
low ed
low intel
low SE status
military combat
GGT how long after alcohol consumption
normal after 8 weeks
aggression transmitters- others
low GABA
high testosterone
high acetylcholine
who has increased risk of TD?
women
people over 50
kids
brain damage
mood disorders
the only anxiety disorder with equal prevalence between genders
OCD
clonazepam
rapid rate of absoprtion
half life of 34 hours- long acting
alprazolam
medium rate of absorption
half life 12 hours
short acting
diazepam
rapid absoprtion
half life 100 hours
long acting
lorazepam
medium rate of absorption
half life 15 hours
short-acting
block H1 receptor–>
weight gain
sedation
block Ach receptor
dry mouth
constipation
blurry vision
urinary retention
cognitive dysfunction
block alpha 1 receptor
orthostatic hypotension
drowsiness
block D receptor
EPS, prolactin
NMS vs serotonin
serotonin syndrome has more myoclonus, GI issues, more likely to possibly have normal CPK
Huntington’s MRI
caudate and cerebral atrophy
TCA that has a metabolite with potent D2 blockade and antipsychotic like AE
amoxapine
percent of population with personality disorder
10-15%
What makes ring enhancing lesions
TB and toxo
stroke causing alexia without agraphia
l posterior cerebral artery
(corpus callosum)
Wellbutrin CYP
2D6 inhibitor
women and alcohol
have less alcohol dehydrogenase in the gut
worst HA and vomiting
subarachnoid
FDA for post herpetic neuralgia
gabapentin
stiff person MOA
anti GAD antibodies (glutamic acid decarboxylase)
test for binary predictor and binary outcome
chi squared
test for binary predictor and continuous outcome
T test
test for two or more binary predictor variables and one continuous outcome
ANOVA
test for one continuous predictor and one continuous outcome variable
correlation
test for two or more continuous or binary variables and one continuous outcome
regression analysis
