Spiegel Flashcards

1
Q

bonding vs attachment

A

bonding: mother for child
attachment: child for mom

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2
Q

huntington’s test

A

PCR

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3
Q

orbitofrontal lesion–>

A

profane, irritable, irresponsible

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4
Q

good enough mother?

A

Winnicott

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5
Q

Wernicke’s in the brain

A

microhemorrhages in perivent gray, esp the aqueduct and 3/4 ventricle

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6
Q

huntington’s disease genetic

A

autosomal dominant. 50% chance any affected carrier passes it on.

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7
Q

primary, secondary, tertiary prevention

A
  1. prevent onset of disease
  2. treatment in early stages (identify)
  3. reduce deficits, obtain highest level of functioning
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8
Q

rx for absence seizures

A
  1. ethosux
  2. VPA
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9
Q

neurotransmitter with increased aggression?

A

dopamine

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10
Q

avg ages puberty

A

girls 11, boys 13

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11
Q

avoid sumatriptan with what medical issues

A

heart disease

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12
Q

use to dx MG

A

edrophonium

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13
Q

Gowers sign?

A

Duchennes

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14
Q

paxil is not

A

sedating

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15
Q

test for temporal cell arteritis

A

ESR

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16
Q

when not to use an MAOi

A

seizures, anorexia, head trauma, bupropion, hypertension

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17
Q

timing for PTSD

A

over one month

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18
Q

phenytoin AE

A

gingival hypertrophy, hirsutism, facial dysmorphia

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19
Q

conversion disorder will involve

A

neurological symptoms

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20
Q

sex play normal before puberty?

A

yes

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21
Q

when will a physical deformity most affect psych?

A

adolescence

22
Q

what is selective to MAO-B at low doses

A

selegeline

23
Q

cocaine and dopamine

A

leads to hypodopaminergic state chronically

24
Q

activation of right prefrontal cortex vs left

A

right leads to depression
left leads to uplifted mood

25
Q

1 cause of intracerebral hemorrhage

A

hypertension

26
Q

type I vs type II error

A

type one: null hypothesis rejected when should have been retained
type two: null hypothesis retained when should have been rejected

27
Q

HIV enceph with CD4 under 200

A

cryptococcal. do lumbar puncture for CSF analysis and india ink staining

28
Q

length of time in urine for PCP, cannabis, cocaine, heroin

A

PCP- 8 days
cannabis 4 weeks
cocaine 8 hours
heroin 72 hours

29
Q

conduction aphasia

A

from left-hemispheric (dominant) lesions esp inf parietal or sup temp regions. Arcuate fasciculus* –> inability to repeat normal, spontaneous speech
possible paraphasic errors and hesitancy
naming may be impaired
auditory comprehension is intact
writing +/-

associated symptoms can include right hemiparesis, right hemisensory loss, right hemianopsia, limb apraxia

30
Q

Broca’s aphasia

A

brocas area- left posterior inferior frontal gyrus
broken, stuttering, staccato speech
inability to repeat
reading often impaired, auditory comprehension usually intact

31
Q

Wernicke’s aphasia

A

lesion superior temporal gyrus in wernicke’s are
Speech fluent, comprehension impaired
logorrheic or overproductive speech
+ nelogisms, verbal paraphasic errors, jargon. Impaired repetition, naming, auditory comprehension, reading. Often + r homonymous hemianopsia with ABSENCE of motor and sensory signs

32
Q

Global aphasia

A

large lesions in superior temporal, inferior frontal, parietal lobes
MCA- usually
Naming, reading, repetition, writing all poor
most + dense right hemiparesis, hemisensory loss, hemianopsia

33
Q

Transcortical aphasia

A

areas around and adjacent to Broca’s and Wernicke’s
telegraphic, stuttering speech; sparing of comprehension, fluent repetition
ACA territory
pt can only repeat

34
Q

rapid sodium replacement in hyponatremia –>

A

central pontine myelinolyses and locked-in syndrome

35
Q

lifetime prevalence of schizophrenia

A

1%

36
Q

aggression associated with

A

decreased serotonin in CSF
increased dopamine
NE, serotonin, GABA inhibit

37
Q

Metachromatic leukodystrophy

A

autosomal recessive
deficiency in arylsulfatase A
accumulation of sulfatides in the brain and nerves –> progressive demyelination.
gait disorder, hypotonia, lower limb atonia

38
Q

Tay-Sachs

A

autosomal recessive gangliosidosis –> hexosaminidase A deficiency
retardation, paralysis, dementia, blindness, deth at 2-3. Cherry red spot on fundoscopic exam. Hypersensitivity to loud noise.

39
Q

Krabbes disease

A

globoid cell leukodystrophy
autosomal recessive
deficiency in galactocerebrosidase B-galactosidase. Chromosome 14
Multinucleated macrophages in central white matter, extensive central and peripheral demyelination
rapid deterioration in motor and intellectual development, hypertonicity, optic atrophy, opisthotonic posture, seizures.

40
Q

reflex that can extend beyond 6 months?

A

parachute

41
Q

tricyclic AEs

A

anticholinergic
dry mouth
blurry vision
sweating
orthostatic hypotension
sedation
lethargy
agitation
tremor
slowed cardiac conduction (PR, QRS)
tachycardia

42
Q

antidepressant that can be used as antipruritic agent and rx gastric ulcer because potent histamine blockade?

A

amitriptyline

43
Q

where is NE made?

A

locus ceruleus

44
Q

where is serotonin made?

A

dorsal raphe nuclei

45
Q

Where is dopamine made?

A

substantia nigra

46
Q

where is acetylcholine made

A

nucleus basalis of meynert

47
Q

drainage of CSF into the blood is a function of the

A

arachnoid granulations

48
Q

subacute sclerosing panencephalitis (SSPE) is a result of a persistent and noproductive viral infection of the neurons and glia that is cause by…

A

measles

49
Q

Sturge-Weber syndrome

A

neurocutaneous disorder
not genetic
port-wine nevus
+/- mental retardation, contralateral hemiparesis, homonymous hemianopia

50
Q
A