Spiegel

Question 1

bonding vs attachment

Answer 1

bonding: mother for child
attachment: child for mom

Question 2

huntington’s test

Answer 2

PCR

Question 3

orbitofrontal lesion–>

Answer 3

profane, irritable, irresponsible

Question 4

good enough mother?

Answer 4

Winnicott

Question 5

Wernicke’s in the brain

Answer 5

microhemorrhages in perivent gray, esp the aqueduct and 3/4 ventricle

Question 6

huntington’s disease genetic

Answer 6

autosomal dominant. 50% chance any affected carrier passes it on.

Question 7

primary, secondary, tertiary prevention

Answer 7

1. prevent onset of disease
2. treatment in early stages (identify)
3. reduce deficits, obtain highest level of functioning

Question 8

rx for absence seizures

Answer 8

2. ethosux
3. VPA

Question 9

neurotransmitter with increased aggression?

Answer 9

dopamine

Question 10

avg ages puberty

Answer 10

girls 11, boys 13

Question 11

avoid sumatriptan with what medical issues

Answer 11

heart disease

Question 12

use to dx MG

Answer 12

edrophonium

Question 13

Gowers sign?

Answer 13

Duchennes

Question 14

paxil is not

Answer 14

sedating

Question 15

test for temporal cell arteritis

Answer 15

ESR

Question 16

when not to use an MAOi

Answer 16

seizures, anorexia, head trauma, bupropion, hypertension

Question 17

timing for PTSD

Answer 17

over one month

Question 18

phenytoin AE

Answer 18

gingival hypertrophy, hirsutism, facial dysmorphia

Question 19

conversion disorder will involve

Answer 19

neurological symptoms

Question 20

sex play normal before puberty?

Answer 20

yes

Question 21

when will a physical deformity most affect psych?

Answer 21

adolescence

Question 22

what is selective to MAO-B at low doses

Answer 22

selegeline

Question 23

cocaine and dopamine

Answer 23

leads to hypodopaminergic state chronically

Question 24

activation of right prefrontal cortex vs left

Answer 24

right leads to depression
left leads to uplifted mood

Question 25

#1 cause of intracerebral hemorrhage

Answer 25

hypertension

Question 26

type I vs type II error

Answer 26

type one: null hypothesis rejected when should have been retained type two: null hypothesis retained when should have been rejected

Question 27

HIV enceph with CD4 under 200

Answer 27

cryptococcal. do lumbar puncture for CSF analysis and india ink staining

Question 28

length of time in urine for PCP, cannabis, cocaine, heroin

Answer 28

PCP- 8 days cannabis 4 weeks cocaine 8 hours heroin 72 hours

Question 29

conduction aphasia

Answer 29

from left-hemispheric (dominant) lesions esp inf parietal or sup temp regions. Arcuate fasciculus* --> inability to repeat normal, spontaneous speech possible paraphasic errors and hesitancy naming may be impaired auditory comprehension is intact writing +/- associated symptoms can include right hemiparesis, right hemisensory loss, right hemianopsia, limb apraxia

Question 30

Broca's aphasia

Answer 30

brocas area- left posterior inferior frontal gyrus broken, stuttering, staccato speech inability to repeat reading often impaired, auditory comprehension usually intact

Question 31

Wernicke's aphasia

Answer 31

lesion superior temporal gyrus in wernicke's are Speech fluent, comprehension impaired logorrheic or overproductive speech + nelogisms, verbal paraphasic errors, jargon. Impaired repetition, naming, auditory comprehension, reading. Often + r homonymous hemianopsia with ABSENCE of motor and sensory signs

Question 32

Global aphasia

Answer 32

large lesions in superior temporal, inferior frontal, parietal lobes MCA- usually Naming, reading, repetition, writing all poor most + dense right hemiparesis, hemisensory loss, hemianopsia

Question 33

Transcortical aphasia

Answer 33

areas around and adjacent to Broca's and Wernicke's telegraphic, stuttering speech; sparing of comprehension, fluent repetition ACA territory pt can only repeat

Question 34

rapid sodium replacement in hyponatremia -->

Answer 34

central pontine myelinolyses and locked-in syndrome

Question 35

lifetime prevalence of schizophrenia

Answer 35

1%

Question 36

aggression associated with

Answer 36

decreased serotonin in CSF increased dopamine NE, serotonin, GABA inhibit

Question 37

Metachromatic leukodystrophy

Answer 37

autosomal recessive deficiency in arylsulfatase A accumulation of sulfatides in the brain and nerves --> progressive demyelination. gait disorder, hypotonia, lower limb atonia

Question 38

Tay-Sachs

Answer 38

autosomal recessive gangliosidosis --> hexosaminidase A deficiency retardation, paralysis, dementia, blindness, deth at 2-3. Cherry red spot on fundoscopic exam. Hypersensitivity to loud noise.

Question 39

Krabbes disease

Answer 39

globoid cell leukodystrophy autosomal recessive deficiency in galactocerebrosidase B-galactosidase. Chromosome 14 Multinucleated macrophages in central white matter, extensive central and peripheral demyelination rapid deterioration in motor and intellectual development, hypertonicity, optic atrophy, opisthotonic posture, seizures.

Question 40

reflex that can extend beyond 6 months?

Answer 40

parachute

Question 41

tricyclic AEs

Answer 41

anticholinergic dry mouth blurry vision sweating orthostatic hypotension sedation lethargy agitation tremor slowed cardiac conduction (PR, QRS) tachycardia

Question 42

antidepressant that can be used as antipruritic agent and rx gastric ulcer because potent histamine blockade?

Answer 42

amitriptyline

Question 43

where is NE made?

Answer 43

locus ceruleus

Question 44

where is serotonin made?

Answer 44

dorsal raphe nuclei

Question 45

Where is dopamine made?

Answer 45

substantia nigra

Question 46

where is acetylcholine made

Answer 46

nucleus basalis of meynert

Question 47

drainage of CSF into the blood is a function of the

Answer 47

arachnoid granulations

Question 48

subacute sclerosing panencephalitis (SSPE) is a result of a persistent and noproductive viral infection of the neurons and glia that is cause by...

Answer 48

measles

Question 49

Sturge-Weber syndrome

Answer 49

neurocutaneous disorder not genetic port-wine nevus +/- mental retardation, contralateral hemiparesis, homonymous hemianopia