Sources of Drug

Question 1

SOURCES OF DRUGS

Answer 1

Plant sources

Animal sources

Mineral/ Earth sources

Microbiological sources

Synthetic/ Semi-synthetic sources

Genetic Engineering

Question 2

PLANT SOURCES

Answer 2

 Plant materials have served as a
reservoir of potential drugs
 Conversion of botanic folklore
remedies into modern wonder drugs
 After isolation and structural
identification of active plant
constituents, it maybe recreated by
total synthesis
 Make use of the natural chemical as
the starting material and modified
them through molecular manipulation

Question 3

Rauwolfia
serpentina

Answer 3

USES:
- Chemical
reserpine
- Tranquilizer
- Hypotensive
agent

Question 4

Vinca rosea

Answer 4

USES:
- Periwinkle
- Antidiabetic
agent
- Antitumor
activity

Question 5

Vitex negundo

Answer 5

USES:
- Lagundi Leaves
are considered
aromatic, bitter,

anti-
inflammatory,

and bronchial
smooth muscle
relaxant

Question 6

Mangostana
garcinia

Answer 6

USES:
- Used to
treat skin
infections,
wounds, dysent
ery, and urinary
tract infections

Question 7

 Drug testing and biologic assay
 Provided drugs that are mannered from their tissues or through their biologic
processes

Answer 7

ANIMAL SOURCES

Question 8

Pancreas is a source of

Answer 8

Insulin,used in treatment of Diabetes.

Question 9

Urine of pregnant women gives

Answer 9

human chorionic gonadotropin (hCG) used for
the treatment of infertility.

Question 10

Sheep thyroid is a source of

Answer 10

thyroxin, used in hypertension.

Question 11

Anterior pituitary is a source of pituitary gonadotropins,

Answer 11

used in treatment of
infertility.

Question 12

Blood of animals is used in preparation of

Answer 12

vaccines.

Question 13

Stomach tissue contains pepsin and trypsin,

Answer 13

which are digestive juices used in
treatment of peptic diseases in the past.

Question 14

MINERAL/ EARTH SOURCES

Answer 14

Metallic and Non metallic sources:

Question 15

is used in treatment of iron deficiency anemia.

Answer 15

Iron

Question 16

Mercurial salts are used in

Answer 16

Syphilis.

Question 17

used in wounds and in eczema.

Answer 17

Zinc is used as zinc supplement.
Zinc oxide paste

Question 18

Iodine is

Answer 18

antiseptic.

Question 19

are used in the treatment of rheumatoid
arthritis.

Answer 19

Gold salts

Question 20

has antiseptic properties.

Answer 20

Fluorine
Borax

Question 21

is used in anti dandruff
shampoos.

Answer 21

Selenium as selenium sulfide

Question 22

is used in preparation of liquid paraffin.

Answer 22

Petroleum

Question 23

 Include serums, antitoxins and vaccines
 In 1796, Edward Genner works on smallpox vaccine

Answer 23

MICROBIOLOGICAL SOURCES

Question 24

Poliomyelitis vaccine-

Answer 24

renal monkey

Question 25

Mumps & Influenza vaccine-

Answer 25

chick embryo

Question 26

Rubella (German measles) vaccine-

Answer 26

duck embryo

Question 27

is a fungus which gives penicillin.

Answer 27

Penicillium notatum

Question 28

give Streptomycin.

Answer 28

Actinobacteria

Question 29

are obtained from streptomycis and micromonosporas

Answer 29

Aminoglycosides such as gentamicin and tobramycin