Sources of Drug Flashcards

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1
Q

SOURCES OF DRUGS

A

Plant sources

Animal sources

Mineral/ Earth sources

Microbiological sources

Synthetic/ Semi-synthetic sources

Genetic Engineering

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2
Q

PLANT SOURCES

A

 Plant materials have served as a
reservoir of potential drugs
 Conversion of botanic folklore
remedies into modern wonder drugs
 After isolation and structural
identification of active plant
constituents, it maybe recreated by
total synthesis
 Make use of the natural chemical as
the starting material and modified
them through molecular manipulation

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3
Q

Rauwolfia
serpentina

A

USES:
- Chemical
reserpine
- Tranquilizer
- Hypotensive
agent

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4
Q

Vinca rosea

A

USES:
- Periwinkle
- Antidiabetic
agent
- Antitumor
activity

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5
Q

Vitex negundo

A

USES:
- Lagundi Leaves
are considered
aromatic, bitter,

anti-
inflammatory,

and bronchial
smooth muscle
relaxant

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6
Q

Mangostana
garcinia

A

USES:
- Used to
treat skin
infections,
wounds, dysent
ery, and urinary
tract infections

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7
Q

 Drug testing and biologic assay
 Provided drugs that are mannered from their tissues or through their biologic
processes

A

ANIMAL SOURCES

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8
Q

Pancreas is a source of

A

Insulin,used in treatment of Diabetes.

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9
Q

Urine of pregnant women gives

A

human chorionic gonadotropin (hCG) used for
the treatment of infertility.

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10
Q

Sheep thyroid is a source of

A

thyroxin, used in hypertension.

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11
Q

Anterior pituitary is a source of pituitary gonadotropins,

A

used in treatment of
infertility.

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12
Q

Blood of animals is used in preparation of

A

vaccines.

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13
Q

Stomach tissue contains pepsin and trypsin,

A

which are digestive juices used in
treatment of peptic diseases in the past.

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14
Q

MINERAL/ EARTH SOURCES

A

Metallic and Non metallic sources:

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15
Q

is used in treatment of iron deficiency anemia.

A

Iron

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16
Q

Mercurial salts are used in

A

Syphilis.

17
Q

used in wounds and in eczema.

A

Zinc is used as zinc supplement.
Zinc oxide paste

18
Q

Iodine is

A

antiseptic.

19
Q

are used in the treatment of rheumatoid
arthritis.

A

Gold salts

20
Q

has antiseptic properties.

A

Fluorine
Borax

21
Q

is used in anti dandruff
shampoos.

A

Selenium as selenium sulfide

22
Q

is used in preparation of liquid paraffin.

A

Petroleum

23
Q

 Include serums, antitoxins and vaccines
 In 1796, Edward Genner works on smallpox vaccine

A

MICROBIOLOGICAL SOURCES

24
Q

Poliomyelitis vaccine-

A

renal monkey

25
Q

Mumps & Influenza vaccine-

A

chick embryo

26
Q

Rubella (German measles) vaccine-

A

duck embryo

27
Q

is a fungus which gives penicillin.

A

Penicillium notatum

28
Q

give Streptomycin.

A

Actinobacteria

29
Q

are
obtained from streptomycis and micromonosporas

A

Aminoglycosides such as gentamicin and tobramycin