Sources of Drug Flashcards
SOURCES OF DRUGS
Plant sources
Animal sources
Mineral/ Earth sources
Microbiological sources
Synthetic/ Semi-synthetic sources
Genetic Engineering
PLANT SOURCES
Plant materials have served as a
reservoir of potential drugs
Conversion of botanic folklore
remedies into modern wonder drugs
After isolation and structural
identification of active plant
constituents, it maybe recreated by
total synthesis
Make use of the natural chemical as
the starting material and modified
them through molecular manipulation
Rauwolfia
serpentina
USES:
- Chemical
reserpine
- Tranquilizer
- Hypotensive
agent
Vinca rosea
USES:
- Periwinkle
- Antidiabetic
agent
- Antitumor
activity
Vitex negundo
USES:
- Lagundi Leaves
are considered
aromatic, bitter,
anti-
inflammatory,
and bronchial
smooth muscle
relaxant
Mangostana
garcinia
USES:
- Used to
treat skin
infections,
wounds, dysent
ery, and urinary
tract infections
Drug testing and biologic assay
Provided drugs that are mannered from their tissues or through their biologic
processes
ANIMAL SOURCES
Pancreas is a source of
Insulin,used in treatment of Diabetes.
Urine of pregnant women gives
human chorionic gonadotropin (hCG) used for
the treatment of infertility.
Sheep thyroid is a source of
thyroxin, used in hypertension.
Anterior pituitary is a source of pituitary gonadotropins,
used in treatment of
infertility.
Blood of animals is used in preparation of
vaccines.
Stomach tissue contains pepsin and trypsin,
which are digestive juices used in
treatment of peptic diseases in the past.
MINERAL/ EARTH SOURCES
Metallic and Non metallic sources:
is used in treatment of iron deficiency anemia.
Iron
