Soft Tissue and Bone Sarcomas

Question 1

Sarcoma associated with a virus

Answer 1

Kaposi’s sarcoma (HIV1)

Question 2

Gene mutation in GISTs

Answer 2

c-kit gene

Question 3

MC presentation of sarcomas

Answer 3

Asymptomatic

Question 4

MC site of metastasis

Answer 4

Lungs

Question 5

MC site of mets of GIST

Answer 5

Liver

Question 6

Treatment for GIST

Answer 6

Imatinib

Question 7

MC malignant tumors of bone

Answer 7

Plasma cell tumors

Question 8

Comprises most of all bone sarcomas

Answer 8

Osteosarcoma

Question 9

Spiculated periosteal reaction in xray

Answer 9

Sunburst appearance

Question 10

Cuff of periosteal new bone formation at the margin of the soft tissue mass in xray

Answer 10

Codman’s triangle

Question 11

Moth-appearance in xray

Answer 11

Osteosarcoma

Question 12

MC site of osteosarcoma

Answer 12

metaphyses if long bones

distal femur, prox tibia and prox humerus

Question 13

Best defines intramedullary and soft tissue extension

Answer 13

MRI

Question 14

Treatment of osteosarcoma

Answer 14

Chemo + limb-sparing surgery

Radioresistant

Question 15

Onion-peel periosteal reaction in xray

Answer 15

Ewing’s sarcoma

Question 16

MC site of Ewing’s sarcoma

Answer 16

Diaphyseal region of long bones, flat bones

Question 17

MC primary sites of metastases

Answer 17

Prostate
Breast
Lung

Question 18

Metastasis mainly yield osteolytic lesion

Answer 18

Kidney Ca

Question 19

Metastasis mainly yield osteoblastic lesion

Answer 19

Prostate Ca