Gynecologic Flashcards
MC type of epithelial ovarian ca
Serous
Tumors that can metastasize to the ovaries
Breast Colon Appendiceal Gastric Pancreatic
Bilateral ovarian masses from GI Ca
Krukenberg tumors
Gene increases risk of ovarian CA
BRCA1
MC stage at presentation
Stage IIIC (bulky intraperitoneal disease)
First sign of relapse of ovarian Ca
Inc CA-125
HER2/neu positive treatment
Trastuzumab
MC hormone-producing tumors
Thecomas
Granulosa cell tumor
juvenile granulosa tumor
Tumor marker for recurrence of epithelial or germ cell tumors
Inc inhibin
Tumor marker for Sertoli-Leydig tumors
a Fetoprotein
MC germ cell neoplasm of the ovary
Benign Teratoma
mc malignant transformation: squamous cell ca
Chemotherapy for Ovarian Ca
Bleomycin, Etoposide, Cisplatin
2nd MC and most lethal malignancy in women
Cervical Ca
Primary neoplastic-initiating event in most woment with invasive cervical Ca
HPV
Most frequent serovars associated with high-grade dysplasia and cancer
HPV 16 and 18