sodium Flashcards
___ are responsible for most of Na+ excretion
kidneys
^ in osmolarity causes __ ECF volume, cause ___ in BP
increase; increase
aldosterone made in ____
adrenal cortex
cytoplasmic aldosterone receptor is a ____ receptor
mineralocorticoid
aldosterone participates in ____ to create new K and Na channels on ___ membrane
transcription; apical
aldosterone secretion mainly stimulated by ___ extracellular [] ___ and ___BP
increased; K+; decreased
aldosterone secretion is inhibited by ___
increased osmolarity
decreased BP causes pathway that results in production of _____
angiotensin2
granular cells are also called _____ cells
juxtaglomerular
what is the purpose fo renin-angiotensin path?
maintaining blood pressure
renin’s main role is to convert _____ into ____
angiotensinogen; angiotensin 1
the enzyme that converts angiotensin 1 into 2
ACE (angiotensin converting enzyme)
what does ANG2 do?
^cardiac output, BP (vasoconstriction), thirst, Na reabsorption of proximal tubule, ADH/vasopressin secretion, absorption of water
what is ANP and what does it do?
increases Na and water excretion; Atrial Natriuretic peptide
hypokalemia causes K+ to move ___, hyperkalemia causes K+ to move ___ cell
outside (hard to depolarize); inside (cause depolarization)