SNRIs/SSRIs

Question 1

Hypertension can occur in high doses. Do not give if pt has uncontrolled or labile htn

Answer 1

Venlafaxine

Question 2

Hepatotoxicity possible in pt with liver disease or heavy alcohol use

Answer 2

Duloxetine

Question 3

Increases HBA1c and blood sugar levels

Answer 3

Duloxetine

Question 4

Fewest drug-drug interactions

Answer 4

Citalopram

Question 5

Dose depended QTc prolongation. EKG before starting and after ending

Answer 5

Citalopram and escitalopram

Question 6

Used for OCD. Highest risk of drug drug interaction

Answer 6

Fluvoxamine

Question 7

Highly protein bound, leading to several drug interactions. Inhibits its own metabolism

Answer 7

Paroxetine

Question 8

More Anticholinergic SEs than other SSRIs

Answer 8

Paroxetine

Question 9

Cardiac defects in pregnancy. Do not use

Answer 9

Paroxetine

Question 10

Approved for OCD control as young as 6 y/o

Answer 10

Sertraline

Question 11

Highest risk of GI and sleep disturbances. Best cardiac safety profile

Answer 11

Sertraline

Question 12

Longest t1/2 of 2.5 weeks

Answer 12

Fluoxetine