SNRIs

Question 1

How do SNRIs work?

Answer 1

SNRI works by preventing the reuptake of serotonin AND norepinephrine back into the presynaptic nerve.

This results in MORE serotonin and norepinephrine being available in the synapse and thus an amplified transmission.

Question 2

Is clinical response of SNRIs gradual or immediate?

Answer 2

gradual

Question 3

Brand name for Venlafaxine

Answer 3

Effexor

Ven al LA to EFF
(Come to LA to EFF).. Venlafaxine

Question 4

Brand name for Desvenlafaxine

Answer 4

Pristiq, Khedezla

Des ven … don’t come to these weird sounding cities.. Desvenlafaxine

Question 5

Brand name for Duloxetine

Answer 5

Cymbalta

You’re so DULL; here are cymbals to bang around! Duloxetine

Question 6

Brand name for Levomilnacipran

Answer 6

Fetzima

Levo / rise for the fet-e! Levomilnacipran

Question 7

What are the SNRIs? (4)

Answer 7

SNRIs: 
•	Desvenlafaxine - Pristiq, Khedezla
•	Levomilnacipran – Fetzima
•	Duloxetine - Cymbalta
•	Venlafaxine – Effexor 

DLDV
DL Doesn’t Voom

Question 8

What are the 3 mixed action antidepressants?

Answer 8

SNRIs, atypical agents, serotonin modulators

Question 9

NE or serotonin: mobilizes body for action; increased blood pressure?

Answer 9

NE

NE mobilizes body for action; increased blood pressure

Question 10

NE or serotonin: love chemical; regulates mood, appetite, sleep

Answer 10

Serotonin

is the love chemical; regulates mood, appetite, sleep

Question 11

Do SNRIs result in MORE or LESS serotonin & NE being available in the synapse?

Answer 11

More

SNRIs result in more serotonin AND norepinephrine being available in the synapse and thus an amplified transmission