MAOIs

Question 1

MAOIs increase/decrease the amount of neurotransmitter than can be released into the synapse leading to more/less action potentials in the post synaptic cell

Answer 1

Increase; more

MAOIs increase the amount of neurotransmitter than can be released into the synapse leading to more action potentials in the post synaptic cell

Question 2

MAO-A or MAO-B inhibition: necessary for antidepressant effects

Answer 2

MAO-A

MAO-A inhibition necessary for antidepressant effects

Question 3

MAO-A or MAO-B inhibition: used in treatment of Parkinson’s

Answer 3

MAO-B

MAO-B inhibition used in treatment of Parkinson’s

Question 4

Which MAO is only selective for MAO-B and has reversible inhibition?

Answer 4

Selegiline

Is Selective for MAO-B, has Reversible Inhibition

Question 5

Brand name for: Isocarboxazid

Answer 5

Marplan

I-so belong on Mars.. Isocarboxazid

Question 6

Brand name for: Phenelzine

Answer 6

Nardil

AmyPhen blogger used Nar-s.. Phenelzine

Question 7

Brand name for: Tranylcypromine

Answer 7

Parnate

Tran-s ppl may go to Parnes.. Tranylcypromine

Question 8

Brand name for: Selegiline

Answer 8

Emsam

Sele-na and EmSam.. Selegiline

Question 9

Main side effects of MAOIs?

Answer 9

Main side effects of MAOIs?

• Tingling in hands and feet
• Interferes w/ Vitamin B6 metabolism
• Overstimulation (wired, jittery, anxious, nervous), esp w/ tranylcypromine