SNC Flashcards

1
Q

cuales son los objetvos terapeuticos del snc

A
  • Canales iónicos que regulan los cambios en la excitabilidad inducida por neurotransmisores
  • Receptores de neurotransmisores que responden fisiológicamente a la activación por neurotransmisores
  • Proteínas de transporte que recapturan el transmisor liberado
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2
Q

Nuerotransmisores (aminoacidos)

A
  • GABA
  • GLICINA
  • GLUTAMATO
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3
Q

Nuerotransmisores (monoaminas)

A
  • Dopaminas
  • norepinefrina
  • epinefrina
  • histamina
  • serotonina
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4
Q

Neurotrasnmisores (lipidos neuromoduladores)

A

-canabinoides

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5
Q

Neurotrasnmisores (gases)

A

-oxido nitrico, monoxido de carbono

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6
Q

Nuerotransmisores

A
  • Aminoacidos
  • Ach
  • Monoaminas
  • Nueropeptidos
  • purinas
  • Lipidos neuromoduladores
  • gases
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7
Q

CUando el Na entra a la celular resulta

A

despolarizacion

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8
Q

cuadno el K entra a la celula resulta

A

hiperpolarisacion ( no se puede despolarizar)

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9
Q

La Bcuculina es ___ del neurotransmisor ____

A

Antagonista del GABA

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10
Q

Los diazepam es____ del nuerotransmisor

A

agonista del GABA

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11
Q

El GABA y los canales de cloro se encargan de ___ la exitabilidad neurologica

A

reducir

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12
Q

Aminofosfonopentanoato-D

A

antagonista en el receptor de N-Metil de Aspartato

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13
Q

El NMDA es un ___ del receptor de

A

agonista del receptor de glutamato

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14
Q

el NMDA provoca

A

crisis convulcibas ( aumenta exitabilidad)

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15
Q

el sulfato de magnesio se utuiza para la

A

la preclamcia

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16
Q

isquemia liberacion de

A

glutamato

17
Q

glutamato aumenta la

A

aumenta el contenido de calcio

18
Q

Alfa 2 Adrenergicos con efectos agonistas

A
  • reducen la liberacion de los nuerotrasnmisores ( epi nor epi
  • reduce presion arterial
19
Q

Sustancias reguladoras

A
  • Neurotrofinas
  • Neuroesteroides
  • Citosinas
20
Q

Neuroesteroides

A
  • alopregenanolona
  • androstanodiol
  • Dheas