Snake And Spiders

Question 0

Post synaptic neurotoxin

Answer 0

Alpha

Block nicotinic Ach receptor
Asphyxia
Bind with high affinity to alpha

Death adder

Question 1

Pre synaptic neurotoxin

Answer 1

beta

aASAPS
Disrupt synaptic vesicles regeneration
Affect terminal axon
Block release of Ach from terminal
Paralysis of affected muscle 

Slow onset

Tiger snake

Question 2

Pro coagulant toxin

Answer 2

Increase bleeding by consuming clotting factors

Factor 10,9,5
Pro thrombin
Fibrinogen clotting/ consumption

Tiger

Question 3

Anti coagulant

Answer 3

Phospholipids A2 toxin

Protein C anti coagulation
Factor 9,10
Thrombin inhibitor

Mulga

Question 4

Myotoxin

Answer 4

Direct action on myofibrils
Muscle damage
Rhabdomylosis
Renal failure

Tiger

Question 5

Funnel web spider

Answer 5

Robustoxin
Versytixumb

Spontaneous repetitive firing in nerves
Slowing sodium channel inactivation

Only toxic to primates ( IgG plasma inactivation )

Pressure immobilisation, antivenom

Question 6

Red back spider

Answer 6

Alpha latrotoxin

Synaptic vesicles degranulation
Emptying synaptic vesicles
Intense pain, oedema