Smooth Muscle Pharmacology

Question 1

What are the two muscarinic receptor agonists?

Answer 1

acetylcholine and bethanechol

Question 2

What are the two muscarinic receptor antagonists?

Answer 2

atropine and ipratropium

Question 3

What are the alpha adrenergic receptor agonists?

Answer 3

Norepinephrine and epinephrine, phenylephrine, and clonidine

Question 4

What is the alpha adrenergic receptor antagonist?

Answer 4

phentolamine

Question 5

What are the beta adrenergic receptor agonists?

Answer 5

norepinephrine, epinephrine, albuterol, levalbuterol

Question 6

What are the beta adrenergic receptor antagonists?

Answer 6

Propranolol

Question 7

Which are muscarinic and which are nicotinic: ganglion and organ

Answer 7

nicotinic - ganglionic

muscarinic - organ

Question 8

What is the neurotransmitter for parasympathetics?

Answer 8

Ach

Question 9

What is the neurotransmitter for sympathetics?

Answer 9

Norepinephinr

Question 10

What is the difference between mydriasis and miosis?

Answer 10

Miosis is constriction, mydriasis is dilation

Question 11

Muscarinic receptors work by what G protein

?

Answer 11

G q/11

PLC - IP3 - Ca2+

Question 12

alpha 2 and beta adrenergic receptors differ how?

Answer 12

Alpha inhibits the G protein and B excited the G protein

Question 13

Potency and efficacy, how are they represented on the graph?

Answer 13

Further left is higher potency

Higher is higher efficacy

Question 14

Which receptors have a higher potency?

Answer 14

Beta

Question 15

Which receptors have a higher efficacy?

Answer 15

Alpha