Small Mammal Flashcards
SM01-08
name the rodent suborder
mice, rats, gerbils, hamsters, voles, lemmings
myomorphs
name the rodent suborder
guinea pigs, chinchilla, degu
hystricomorph
name the rodent suborder
beavers, kangaroo rats
castrimorpha
name the rodent suborder
anomalures, springhares, zenkerella
anomaluromorph
name the rodent suborder
squirrel
sciuromorph
name the sub-order of Myomorphs
mice and rats
Muridae
name the sub-order of Myomorphs
hamsters and gerbils
Cricetidae
what is the diet of mice and gerbils?
omnivorous
how to sex a rodent?
anogenital distance and number of openings
name the rodent sex
two ‘openings’
greater ano-genital distance
male
(usually very obvious testicles)
name the rodent sex
three ‘openings’
shorter ano-genital distance
female
(separate vaginal and urethral opening)
name 2 specific anatomy considerations for male rodents
- open inguinal canals
- os penis
name the 5 key parts of a rodent clinical exam
- demeanour
- HR and RR
- Nose to tail
- ventrum
- weight and BCS
what is remy?
a RRRRRRAT
what are the 2 main non-infectious cause of diarrhoea in mice
- sudden diet change
- engorgement of food
name 2 viral causes of diarrhoea in rodents
- mouse hepatitis virus (Coronavirus)
- epizootic diarrhoea virus of infant mice (Rotavirus)
name 6 bacterial causes of diarrhoea in mice
- Tyzzer’s disease (Clostridium piliforme)
- C. perfringens and C. difficile
- E. coli
- Lawsonia intracellularis
- Corynebacterium kutscheri
- Helicobacter
name 3 endoparasites that cause diarrhoea in mice
- pinworms (Syphacia obvelata)
- Cryptosporidium
- Giardia
name 4 clinical signs of heavy infestations of pinworms (Synphacia obvelata) in mice
- diarrhoea
- straining leading to rectal prolapse
- unkept fur coat
- anal pruritis
what is the treatment for pinworms (Synphacia obvelata) in mice
Fenbendazole
name 6 aspects of supportive care that can be given to mice with diarrhoea
- fluid therapy
- probiotics
- kaolin
- bismuth subsalicylate
- warmth
- analgesia (not NSAIDs)
name 3 antibiotics that can be used to treat bacterial diarrhoea in mice (and all myomorph species)
- trimethoprim sulphate
- enrofloxacin
- oxytetracycline (Tyzzer’s)
what is the average lifespan of mice?
1-2.5y
when do mice reach sexual maturity
6-8wks
(2mo)
what is the gestation period of mice?
19-21d
what is the litter size for mice
5-12
name 4 predisposing factors of mammary gland neoplasia in mice
- stress
- hormones
- carcinogens
- retroviruses
this is a possible sequelae of ejaculatory plugs in male mice (normal finding) if obstructive to urine flow
(uncommon)
hydronephrosis
what is the most common cause of morbidity in laboratory mice?
respiratory disease
name 3 bacterial causes of respiratory disease in mice
- Mycoplasma pulmonis
- Crynebacterium kutscheri
- Pasteurella pneumotropica
name 2 viral causes of respiratory disease in mice
- Sendai virus
- PVM (pneumonia virus of mice)
name 3 fur mites affecting mice
- Myobia mudculi
- Mycoptes musculinus
- Radfordia affinis
name the fur mite affecting mice
23d lifecycle;
varying severity;
alopecia, self trauma, greasy coat;
head, neck, flank, lateral thorax
Myobia musculi
name the fur mite affecting mice
8-14d lifecycle;
back and ventrum
Mycoptes musculinis
what is the treatment for fur mites in mice?
two doses Ivermectin 10-14d apart
(200-400 IU/kg)
name the skin disease in mice
intense pruritis;
head and thorax;
significant self trauma;
dermal ulceration, necrosis and fibrosis;
cause: vasculitis - immune complex deposits on dermal vessels
idiopathic ulcerative dermatitis
name the skin disease in mice
annular constriction of the tail;
pups more likely to be affected than adults;
low environmental humidity;
oedema, necrosis and sloughing;
Tx: amputation
Ringtail
this is a normal finding in rodent urinalysis
proteinuria
name 5 possible urinary tract diseases in mice
- amyloidosis
- interstitial nephritis
- chronic glomerulonephritis
- leptospirosis
- obstructive uropathies
name the unique anatomy of gerbils
used for territory marking;
rubbing abdomen;
sebaceous gland;
larger and more prominent in sexually mature males
ventral scent gland with orange secretion
why should gerbil NEVER be restrained by the tail
high risk of de-gloving injury
name 2 common conditions of gerbils that can be identified on clinical exam
- masses of ears and scent glands
- cystic ovarian disease in females
what is the average lifespan of gerbils
2-4y
when do gerbils reach sexual maturity
6-8wks
what is the gestation period of gerbils
23-26d
what is the litter size of gerbils
3-8
what is the weaning age of gerbils
20-30d
name the cause of diarrhoea in gerbils
most commonly reported fatal infectious disease in gerbils;
sub-optimal husbandry, weaning and immunosuppression;
oral route of infection;
diarrhoea, anorexia, dehydration and death;
bacterial spores survive for 1y+ at room temp
Tyzzer’s disease
(Clostridium piliforme)
what neurological disease are gerbils predisposed to due to deficiency of cerebral glutamine synthesis
Epilepsy
name the cause of head tilt in gerbils
common in aging rodents;
keratinising epithelial mass;
bone destruction;
secondary otitis media/interna
aural neoplasia - cholesteatoma
how common is cystic ovarian disease in gerbils?
50% females over 400d old
how to treat cystic ovarian disease in gerbils?
ovariohysterectomy
this is the most common tumour of pet gerbils, and most frequently reported neoplasia in lab gerbils;
more common in older animals;
metastasise in the abdomen;
incidence higher in non-breeding females
ovarian granulosa cell tumours
name the gland
located in the retrobulbar space;
plays an important role in tehrmoregulation;
lipids insulate from cold and wet;
lipids and protoporphyrin pigments get mixed with salive and groomed on the coat
Harderian gland
this should be available to rodents to promote normal skin and fur coat health
sand bath
name 3 conditions in rodents that deprivation of sand baths can lead to
- nasal dermatitis
- behavioural issues
- unkept fur coat
name 4 causes of Barbering (skin disease) in gerbils
- stress
- overcrowding
- dominant behaviour
- weight loss from competition of food resources
how much urine does a gerbil pass each day?
2-4 drops per day
name 5 clinical signs of chronic renal disease in gerbils
- PU/PD
- weight loss
- anorexia
- lethargy
- secondary signs of infection
start of SM02
what colour of myomorph (hamsters, etc) incisors
yellow
will the upper or lower incisors of myomorphs (hamsters etc) be longer?
lower
name the part of the hamster
highly distensible invaginations of the buccal mucosa;
cover the masseter muscles, lateral neck and shoulder muscles
cheek pouches
name the 2 parts of a hamster stomach
- non-glandular forestomach
- glandular stomach
name 2 types of bacteria found in the caecum of a hamster
- bacteroides
- lactobacillus
where is the sebaceous scent gland located in dwarf hamsters?
ventral
where is the sebaceous scent gland located in Syrian hamsters?
flank
name 3 underlying causes of cheek pouch impaction in hamsters
- inappropriate food material
- bedding
- incisor malloclusion
name 4 causes of diarrhoea in hamsters
- sudden dietary change
- bacterial
- parasitic
- iatrogenic
name the GIT disease in hamsters
watery foul-smelling diarrhoea, dehydration, death within 3-8wks;
rectal prolapse and intussusception common;
palpably thickened bowel
‘wet tail’
(Lawsonia intracellularis)
name 2 PM signs at the terminal ileum to definitively diagnose ‘wet tail’ in hamsters
- hyperplasia of mucosa
- musle hypertrophy
what is the prognosis for ‘wet tail’ in hamsters
Tx often unsuccessful;
death in 24-48h
name the GIT disease in hamsters, guinea pigs and chinchillas
usually iatrogenic - inappropraite abx (penicillins, clindamycin, lincomycin, eryhtromycin);
dysbiosis leads to overgrowth of C. spiriforme and C. difficile;
Tx: fluids, warmth, Cholestryamine, metronidazole, probiotics
clostridial enterotoxaemia
what is the most common endocrine disease in hamsters?
hyperadrenocorticism
name the 3 variations of hyperadrenocorticism in hamsters
- pituitary dependent
- adrenal dependent
- iatrogenic
name 6 clinical signs of hyperadrenocorticism in hamsters
- bilateral alopecia of the flank/thigh
- skin thinning
- hyperpigmentation of the skin
- hepatomegaly
- polydipsia/polyuria
- behavioural changes
what is the normal plasma cortisol levels of hamsters
13.8-27.6 nmol/L
what is the normal alkaline phosphatase on biochemsitry for hamsters
8-18 IU/L
name 2 medical treatments for hyperadrenocorticism in hamsters
- Metapyrone (8mg/kg PO q24h for 30d)
- Mitotane (5mg PO q24h for 30d) - poor results
which hamster breed is predisposed to Diabetes Mellitus;
autosomal recessive, polygenic
Chinese hamster
name 4 clinical signs of Diabetes Mellitus in hamsters
- PU/PD
- weight loss
- glucosuria
- polyphagia
what is the normal glucose level for hamsters?
7 mmol/L
(diabetic over 16)
what is the average lifespan for hamsters
1.5-2y
when do male hamsters reach sexual maturity
2mo
when do female hamsters reach sexual maturity
1.5mo
what is the gestation period of Syrian hamsters
16-18d
what is the gestation period of Russian hamsters
18-21d
what is the gestation period of Chinese hamsters
21-23d
what is the gestation period of Roborovski hamsters
23-30d
what is the litter size for hamsters
3-10
how long is the oestrus cycle for hamsters
4 days
name the CV disease in hamsters
reported in lab hamsters ;
onset of disease is earlier in females than males;
gender incidence is the same though;
most common in left atrium, secondary to heart failure
atrial thrombosis
name 4 clinica signs of cardiomyopathy in hamsters
- tachypnoea
- lethargy
- anorexia
- cold extremities
how to diagnose cardiomyopathy in hamsters
thoracic radiographs under inhalation anaesthetic
name 2 mites affecting hamsters
- Demodex criceti (short and fat body)
- Demodex aurati (cigar shaped)
name 2 treatments for Demodex mites on hamsters
- subcutaneous ivermectin
- bathing with amitraz, benzoyl peroxide shampoo
name 4 clinical signs of Demodex mites in hamsters
- underlying disease causing immunosuppression
- moderate to severe alopecia
- scale
- erythema
(usually non-pruritic)
name 2 causes of Dermatophytosis (ringworm) in hamsters
- Trichophyton mentagrophytes
- Microsporum sp.
name 3 clinical signs of dermatophytosis (ringworm) in hamsters
- alopecia
- crust
- erythema
(asymptomatic carriers!)
what is the treatment for ringworm in hamsters
itraconazole, topical enilconazole
what are the most common neoplasia causing skin disease in hamsters?
melanomas and melanocytomas
what is the most common neoplasm in hamsters?
lymphoma
name 3 forms of lymphoma in hamsters
- multicentric
- cutaneous
- epizootic
name the 3 main organs affected by multicentric form of lymphoma in hamsters
- spleen
- lymph nodes
- liver
name 5 clinical signs of cutaneous lymphoma in hamsters
- alopecia
- pruritis
- flakey skin
- cutaneous plaques
- ulceration
name the cause of transmissible lymphoma and cutaneous epitheliomas in hamsters;
wart-like lesions around the eyes, mouth or perianal in 3-12mo old hamsters;
highly infectious, transmitted via urine;
long incubation period, very resistant in environment
hamster polyomavirus (HaPV)
start of SM03
how many teeth do rats have?
16
what is the dental formula of rats
2x (I 1/1, C 0/0, PM 0/0, M 3/3)
secretion of this from the Harderian glands of rats results in chromodacryorhea or ‘red tears’;
occur due to stress or disease
porphyrins
why is incisor overgrowth commonly misdiagnosed in rats?
lower incisors normally much longer than upper
name the GI disease in rats
‘mumps’
caused by a Coronavirus;
highly contagious between rats;
direct contact - aerosols;
affects cervical salivary glands leading to inflammation and oedema;
rhinitis and epithial necrosis
Sialodacryoadenitis virus - Parker’s
name 4 clinical signs of Sialodacryoadenitis virus in rats relating to the disruption of lacrimal system
- conjunctivitis
- corneal ulceration
- keratitis
- synechiae
name 3 diagnostics for Sialodacryoadenitis virus in rats
- phenol red thread test
- fluorescein dye
- tonometery (IOPs)
name the musculoskeletal disease of rats
causes avascular necrosis of the femoral head;
predisposing factors: young rats, standing up on hind limbs for long periods of time;
Tx as in canines
Legg-Calve-Perthes disease
name the musculoskeletal disease of rats
degenerative myelopathy;
old rat;
owners notice altered gait;
progressive loss of function: loss of tail control, urinary incontinence, muscle wastage, weight loss, ultimately paresis and paralysis
radiculoneuropathy
what is the treatment for radiculoneuropathy in rats
anti-inflammatory medication
name 5 environmental changes that can be made for rats with radiculoneuropathy
- fleece bedding
- lower hammocks
- reduce height of food and water
- bottom baths to manage urine staining and prevent scald
- separate feeding time
name 4 causes of head tilt in rats
- otitis
- CNS infection
- CNS lesion
- aural foreign body
what is the average lifespan of rats
2-3.5y
when do rats reach sexual maturity
1mo
what is the oestrus cycle of rats
continupus polyoestrus
what is the gestation period of rats
21-23d
what is the litter size for rats
6-13
what is the weaning age of rats
21d
what type of tumours are the majority of mammary tumours in rats?
80% fibroadenoma
(benign)
name 4 consequences that could occur if mammary tumours are not removed from rats
- mechanical alopecia
- erosion and ulceration
- secondary infection
- pain and self trauma
name 2 ways to prevent mammary tumours in rats
- early neutering
- deslorelin hormonal implant
name the 3 main respiratory pathogens in rats
- Mycoplasma pulmonis
- Streptococcus pneumoniae
- Corynebacterium kutscheri
name the 2 main respiratory syndromes in rats
- CRD - Chronic Respiratory Disease
- Bacterial pneumonia
what is the major pathogen of chronic respiratory disease (CRD) in rats
Mycoplasma pulmonis
name 6 clinical signs of chronic respiratory disease (CRD) in rats
- nasal discharge
- ‘rattly-bubbly’ resp
- coughing/sneezing
- dyspnoea/abd effort
- red tears
- weight loss