Small intestine Flashcards

1
Q

What is the small intestine also called?

A

The small bowel

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2
Q

What are the 3 parts of the small intestine?

A

Dueodenum
Jejenum
Ileum

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3
Q

What is the function of the small intestine?

A

The small intestine is the primary site for digestion and absorption

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4
Q

The small intestine is partially retro-peritoneal. What does this mean?

A

Part of it is (duodenum) behind the peritoneum

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5
Q

How long is the small intestine?

A

6.5m

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6
Q

How long is the large intestine?

A

1.5m

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7
Q

The small intestine is longer than the large intestine. Why is it termed the small intestine?

A

The diameter of the small intestine is smaller than that of the large intestine

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8
Q

What are the 2 parts of the peritoneum?

A

Visceral (around the organs) and parietal (outer aspect)

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9
Q

What is the peritoneum?

A

Serous membrane that lines the abdominal cavity

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10
Q

What is the mesothelium?

A

Cells of the peritoneum (serous membrane), produces a watery fluid

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11
Q

Describe the endothelium lining the peritoneum

A

Mesothelium: simple squamous layer of cells

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12
Q

What are double folds of the peritoneum termed?

A

Mesentery

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13
Q

What is the omentum?

A
  • Fold of peritoneum attached to stomach, fatty layer containing lymphatics, blood vessels, nerves
  • Localises on groin on the right hand side
    Infections contained within the omentum
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14
Q

Where does chyme pass from?

A

From the stomach to the duodenum of the small intestine

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15
Q

Describe features of the duodenum

A
  • Short length
  • Contains Brunner’s glands: alkaline secretion
  • Receives common bile duct (sphincter of Oddi) - bile and pancreatic juice enter here
  • Ends at the duodenojejunal junction
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16
Q

What is the purpose of Brunner’s glands in the duodenum?

A

Produce alkaline secretions for protection (gastric fluid is very acidic, pH 1-2)

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17
Q

What is bile for?

A

Fat digestion

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18
Q

What do pancreatic juices do?

A

Protein digestion

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19
Q

What is pancreatitis?

A

Inflammation of the pancreas

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20
Q

Which vertebrae does the duodenum lie between?

A

L1-L4

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21
Q

What shape is the duodenum?

A

C shaped

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22
Q

What is the spinchter of Oddi?

A

Surrounds the major duodenal papilla

Bile and pancreatic juices enter the duodenum at the major duodenal papilla

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23
Q

What percentage of people also have a minor duodenal papilla in addition to a major duodenal papilla?

A

20%

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24
Q

Which hormone controls bile secretions from the gallbladder?

A

Cholecystokinin (CCK)

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25
Which cells secrete CCK?
Cells lining the duodenum
26
What do cells lining the duodenum secrete CCK in response to?
High fat content in the diet
27
What is the advice for patients who have had their gallbladder removed?
Eat less fat in the diet
28
What are the 4 parts of the duodenum?
Superior, descending, inferior, ascending
29
What does the superior mesenteric artery supply?
The midgut Structures like the small intestine, the large intestine Comes straight from the abdominal aorta - largest artery in the body
30
What is the largest artery in the body?
Abdominal aorta
31
What is the first major branch of the abdominal aorta?
Coeliac trunk/coeliac artery
32
Which structures does the superior pancreaticoduodenal artery supply?
The pancreas and the duodenum
33
How many blood supplies does the duodenum have?
2 | C shaped: 1 at top, 1 at bottom
34
What does the inferior pancreaticoduodenal artery supply?
Pancreas and duodenum
35
What are the 2 blood supplies for the duodenum?
1. Superior pancreaticoduodenal artery (from the coeliac trunk of the abdominal aorta) 2. Inferior pancreaticoduodenal artery (from the superior mesenteric artery)
36
What is a duodenal ulcer and where does it arise?
- Most develop in the posterior wall of the superior part of the duodenum (where the stomach acid comes in) - Ulcer is a breakdown of epithelium Possibility of perforation - Can cause peritonitis - life-threatening
37
What is peritonitis?
Inflammation of the peritoneum
38
What might a duodenal ulcer indicate?
Cancer
39
What does air in the abdominal cavity indicate (on an X-ray)?
Something has burst | There should not be air in the abdominal cavity
40
Which part of the small intestine is retro-peritoneal?
Duodenum
41
Which part(s) of the small intestine are within the peritoneum?
Jejenum and ileum
42
What is the function of the duodenum?
Mainly digestion | Pancreatic enzymes and bile
43
What is the function of the jejenum?
Digestion (brush border enzymes) | Absorption
44
What is the function of the ileum?
Mainly absorption
45
Describe the structure/layers of the jejenum and ileum
Lumen, mucosa, submucosa, muscularis externa, adventitia
46
What are the layers of the mucosa?
Epithelium, lamina propria, muscularis mucosae
47
What are the layers of the muscularis externa?
``` Innermost oblique (stomach ONLY) Inner circular Outer longitudinal ```
48
Which nerves supply the small intestine?
Submucosa plexus (meissner plexus) and the myenteric plexus (auerbach plexus)
49
Where is the submucosa plexus located?
In the submucosa
50
Where is the myenteric plexus located?
Between the inner and outer layers of the muscularis externa
51
What can happen is nerves don't develop properly in the small intestine?
Can't contract, can't digest properly, can't absorb properly
52
What are plicae circulares?
Transverse folds | Big folds of the mucosa that can be seen with the naked eye
53
What is the function of plicae circulares?
Increase the surface area of the jejenum and ileum by 1.6-2x Almost doubles the surface area of the small intestine
54
What do microvilli do?
Small projections that increase the surface area by up to 200x for absorption Found in the duodenum, jejenum and ileum
55
What are vasarecta and where are they found?
Straight blood vessels found at the top of the small intesitne
56
Why are the blood vessels more complex/more bendy at the bottom of the small intestine compared to the top?
More absorption going on, increases absorption
57
Infections in the bowel can destroy microvilli. What effect will this have on small bowel function?
Reduced absorption
58
What are Peyer's patches?
Collections of inflammatory tissue | More in the ileum compared to duodenum and jejenum
59
What are enterocytes?
Cells of the intestinal lining
60
What do enterocytes do in the small intestine?
- Digestion (brush border enzymes on microvilli) | - Absorption (carrier proteins)
61
What can malabsorption syndromes cause?
Deficiencies that affect blood e.g. anaemia
62
What is Meckel's diverticulum?
An outpouching in the small intestine | Rule of 2's: 2% of the population affected, get them at 2 years old, 2 feet away from ileocaecal valve, 2 inches long
63
What type of mucosa does Meckel's diverticulum affect?
Mostly ileal mucosa
64
What type of mucosa may be present in the outpouching in Meckel's diverticulum?
Acid producing gastric, pancreatic or colonic type mucosa