SM_210a: Transplant

Question 1

Kidney transplant is _____ effective than dialysis

Answer 1

Kidney transplant is more effective than dialysis

Question 2

_____ donor is most effective kidney transplant

Answer 2

Living donor is most effective kidney transplant

Question 3

Kidney allocation system balances the principles of _____ and _____

Answer 3

Kidney allocation system balances the principles of justice and medical utility

• Principle of justice: recognizes patients with greatest need - prioritizes pediatric patients, patients waiting the longest, and patients who are highly sensitized
• Principle of medical utility: provides greatest good for greatest number - promotes longest survival of organs, minimizes wastage of organs

Question 4

Describe kidney distribution priorities

Answer 4

Kidney distribution prioritizes

1. Hardest to match
2. Sickest: multiple transplants
3. Best outcome: zero antigen mismatch
4. Most deserving: prior living donors
5. Most urgent: pediatrics

Question 5

Principle of longevity is ____

Answer 5

Principle of longevity is giving the longest lasting kidneys to the longest living recipients

Question 6

______ is the argument that everyone should get the chance to live the same length of time

Answer 6

Fair innings is the argument that everyone should get the chance to live the same length of time

Question 7

Chronic immunosuppression is required to prevent ______ but increases risk of ______ and ______

Answer 7

Chronic immunosuppression is required to prevent rejection but increases risk of opportunistic infections and malignancy

Question 8

Disparities based on _____ in addition to race and income exist

Answer 8

Disparities based on geography in addition to race and income exist

Question 9

Elevated serum Cr after kidney transplant is ____

Answer 9

Elevated serum Cr after kidney transplant is broad

Question 10

_____ induces tolerance

Answer 10

Chimerism induces tolerance

(chimera: coexistence of two genetically distinct components in one organism)