SM_188a: Development Flashcards
Nephron tubules, Bowman’s capsule, and the podocytes develop from the _______
Nephron tubules, Bowman’s capsule, and the podocytes develop from the metanephric mesenchyme
Renal vasculature develops from ______
Renal vasculature develops from endothelial progenitors
Collecting ducts, collecting system, and ureter develop from the ______
Collecting ducts, collecting system, and ureter develop from the ureteric bud
Urinary bladder develops from the _____
Urinary bladder develops from the cloaca
Describe the iterations of the kidney
- Pronephros
- Mesonephros
- Metanephros
Primitive kidneys are ______ and ______
Primitive kidneys are pronephros and mesonephros
_______ is the permanent kidney
Metanephros is the permanent kidney
Metanephros is composed of the ______ and ______
Metanephros is composed of the metanephric mesenchyme and ureteric bud
Metanephric mesenchyme and ureteric bud arise from the _______
Metanephric mesenchyme and ureteric bud arise from the intermediate mesoderm
(both form the metanephros)
Metanephric mesenchyme gives rise to ______ that subsequently develop into ______, ______, and ______
Metanephric mesenchyme gives rise to nephron progenitor cells that subsequently develop into the nephron tubules, Bowman’s capsule, and podocytes
Ureteric bud gives rise to ______, ______, ______, and ______
Ureteric bud gives rise to the collecting ducts, calyces, pelvis, and ureter
Kidneys develop from the _____ layer of the embryo
Kidneys develop from the intermediate mesoderm layer of the embryo
Ureteric bud branches and gives rise to ______ via ______
Ureteric bud branches and gives rise to collecting system via branching morphogenesis
Nephron develops from the ______
Nephron develops from the metanephric mesenchyme
Describe the evolution of the nephron
- Renal vesicle
- Comma shape body
- S-shaped body
- Capillary loop
Renal agenesis results from faulty development of _____
Renal agenesis results from faulty development of intermediate mesoderm
Eagle Barret syndrome includes ______, ______, and ______
Eagle Barret syndrome includes undescended testes (bilateral cryptorchidism), poor development of the abdominal muscles, and bilateral hydronephrosis
(massive urinary tract malformations cause chronic kidney disease)
Potter sequence includes ______, ______, and ______
Potter sequence includes flat facies, clubfeet, and polyhydramnios
(causes bilateral renal agenesis, major cause of death is lung hypoplasia)
Abnormal ascent of the kidney may result in ______ and ______
Abnormal ascent of the kidney may result in horseshoe kidney and pelvic kidney
Cyst in the midline below the umbilicus might be a remnant of the ______
Cyst in the midline below the umbilicus might be a remnant of the allantois
Metanephros is made of ______ and ______
Metanephros is made of nephrogenic cord and nephric duct
- Nephrogenic cord -> metanephric mesenchyme -> nephron tubules, Bowman’s capsule, and podocytes
- Nephric duct -> ureteric bud -> collecting duct and collecting system
_______ -> metanephric mesenchyme -> nephron tubules, Bowman’s capsule, and podocytes
Nephrogenic cord -> metanephric mesenchyme -> nephron tubules, Bowman’s capsule, and podocytes
______ -> ureteric bud -> collecting duct and collecting system
Nephric duct -> ureteric bud -> collecting duct and collecting system
______ -> renal vesicle -> comma-shaped body -> S-shaped body -> distal tubule, loop of Henle, proximal tubule, podocytes
Nephron progenitors -> renal vesicle -> comma-shaped body -> S-shaped body -> distal tubule, loop of Henle, proximal tubule, podocytes
