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MSK-Derm by Minnie > SM 218a - Cartilage Histology > Flashcards

SM 218a - Cartilage Histology Flashcards

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Dermatology Board Prep flashcards
1
Q

Which cells produce the matrix that makes up cartilage?

A

Chondrocytes

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2
Q

What is the role of hyaluronic acid in the extracellular matrix?

A

Hyaluronic acid = larges glycosaminoglycan in the matrix

  • Forms complexes with negative charges
  • Binds with water to give the matrix viscosity, strength, and flexibility
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3
Q

Where i shyaline cartilage found?

A
  • Respiratory tube
  • Costal cartilage
  • Cartilage in the nose
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4
Q

Which number labels a lacunar space?

A

1

https://peir-vm.path.uab.edu/wsi.php?slide=UAB-Histology-00002

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5
Q

What structure does #4 indicate?

A

Interterritorial matrix

https://peir-vm.path.uab.edu/wsi.php?slide=UAB-Histology-00002

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6
Q

What structure does #3 indicate?

A

Territorial matrix

https://peir-vm.path.uab.edu/wsi.php?slide=UAB-Histology-00002

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7
Q

What are the 3 types of cartilage?

Describe the composition of each

A
  • Hyaline cartilage
    • Collagen - Type II is the most abundant
    • Proteoglycans
    • Chondrocytes
  • Elastic cartilage
    • Has elastic fibers within the matrix
  • Fibrocartilage
    • Has Type I collagen fibers running through the matrix
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8
Q

Which of the followign would be present in the meniscus but not in the trachea?

  1. Bands of Type I collagen
  2. Elastic fivers
  3. Type II collagen
  4. Hyaluronic acid
  5. Water
A

A. Bands of Type I collagen

  • Meniscus
    • Fibrocartilage; contains bands of Type I collagen
  • Trachea
    • Hyaline cartilage; no type I collagen or elastic fibers
  • All cartilage
    • ​Type II collagen, hyaluronic acid, and water
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9
Q

Where is fibrocartilage found?

A
  • Intervertebral discs
  • Meniscus
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10
Q

What kind of cartilage is this?

(Two different stains shown)

A

Elastic cartilage

(Elastic stains show elastic fibers in black)

https://peir-vm.path.uab.edu/wsi.php?slide=UAB-Histology-00111

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11
Q

What kind of cartilage is this?

A

Hyaline cartilage

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12
Q

Which type of cartilage is most prevalent in the human body?

A

Hyaline

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13
Q

What is the difference between territorial and Interterritorial matrix?

A
  • Territorial
    • Newer
    • Found near chondrocytes
    • Darker staining
  • Interterritorial
    • More mature
    • Found further away from chondrocytes
    • Lighter staining
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14
Q

Where is elastic cartilage found?

A
  • Epiglottis
  • External ear cartilage
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15
Q

What structure does #2 indicate?

A

Chondrocyte

https://peir-vm.path.uab.edu/wsi.php?slide=UAB-Histology-00002

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16
Q

Chondrocytes are found in _____ spaces

A

Chondrocytes are found in lacunar spaces

17
Q

Which kind of cartilage has a “herringbone pattern?”

A

Fibrocartilage

Found in intervertebral disks and the meniscus

18
Q

Describe the composition of cartilage

A

Cartilage = Chondrocytes + Surrounding matrix

  • Matrix
    • ​Water + Collagen + Proteoglycans + Glycosaminoglycans
    • Collagen is mostly type II
    • Most importatn glycosaminoglycan is
  • *hyaluronic acid**
19
Q

What are the functions of cartilage?

A
  • Support the body
  • Articulate joints
  • Provide attachment sites for muscles
  • Improve flexibility
  • Act as a scaffold for bone development
20
Q

What type of cartilage comprises the meniscus?

A

Fibrocartilage

21
Q

What type of tissue is cartilage?

A

Connective tissue

22
Q

What kind of cartilage is this?

A

Fibrocartilage

  • Alternating layers in a herringbone pattern
  • Collagen runs though the layers giving fibrocartilage resistance to compressive forces (ex: in intervertebral discs)

http://virtualslides.med.umich.edu/Histology/Basic%20Tissues/Cartilage%20and%20Bone/045_HISTO_40X.svs/view.apml?cwidth=817&cheight=1021&chost=virtualslides.med.umich.edu&csis=1&X=0&Y=0&zoom=4.09417768499188&listview=1

23
Q

What structure does #5 indicate?

A

Isogenous groups

https://peir-vm.path.uab.edu/wsi.php?slide=UAB-Histology-00002

24
Q

Collagen running through fibrocartilage in layers gives the intervertebral disk resistance to __________ forces

A

Collagen running through fibrocartilage in layers gives the intervertebral disk resistance to compressive forces

MSK-Derm by Minnie (48 decks)

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